1HNE

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-angstroms resolution

Summary for 1HNE

Entry DOI	10.2210/pdb1hne/pdb
Related PRD ID	PRD_000402
Descriptor	HUMAN LEUCOCYTE ELASTASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALA CHLOROMETHYL KETONE INHIBITOR (3 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	23796.92
Authors	Navia, M.A.,Mckeever, B.M.,Springer, J.P.,Lin, T.-Y.,Williams, H.R.,Fluder, E.M.,Dorn, C.P.,Hoogsteen, K. (deposition date: 1989-04-10, release date: 1989-10-15, Last modification date: 2012-12-12)
Primary citation	Navia, M.A.,McKeever, B.M.,Springer, J.P.,Lin, T.Y.,Williams, H.R.,Fluder, E.M.,Dorn, C.P.,Hoogsteen, K. Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution. Proc.Natl.Acad.Sci.USA, 86:7-11, 1989 Cited by PubMed: 2911584 DOI: 10.1073/pnas.86.1.7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation