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1HNE

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-angstroms resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
HUMAN LEUCOCYTE ELASTASEpolymer21823320.01UniProt (P08246)
Pfam (PF00089)
Homo sapiens (human)
2B
(I)
METHOXYSUCCINYL-ALA-ALA-PRO-ALA CHLOROMETHYL KETONE INHIBITORpolymer6477.01BIRD (PRD_000402)
3C, D
(E, I)
waterwater18.0225Chemie (HOH)
Sequence modifications
E: 16 - 243 (UniProt: P08246)
PDBExternal DatabaseDetails
Asp 91Asn 107conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight23796.9
All*Total formula weight23796.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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