2PHI

A LARGE CONFORMATIONAL CHANGE IS FOUND IN THE CRYSTAL STRUCTURE OF THE PORCINE PANCREATIC PHOSPHOLIPASE A2 POINT MUTANT F63V

Summary for 2PHI

DescriptorPHOSPHOLIPASE A2, CALCIUM ION (3 entities in total)
Functional Keywordshydrolase (carboxylic ester)
Biological sourceSus scrofa (pig)
Cellular locationSecreted P00592
Total number of polymer chains2
Total molecular weight28043.58
Authors
Dijkstra, B.W.,Thunnissen, M.M.G.M.,Kalk, K.H.,Drenth, J. (deposition date: 1993-04-08, release date: 1993-07-15, Last modification date: 2012-01-25)
Primary citation
Thunnissen, M.M.,Franken, P.A.,de Haas, G.H.,Drenth, J.,Kalk, K.H.,Verheij, H.M.,Dijkstra, B.W.
Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
J.Mol.Biol., 232:839-855, 1993
PubMed: 8355274 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1993.1435
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers151.6%10.5%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2phi
no rotation
Molmil generated image of 2phi
rotated about x axis by 90°
Molmil generated image of 2phi
rotated about y axis by 90°