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8FFI
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BU of 8ffi by Molmil
Structure of tetramerized MapSPARTA upon guide RNA-mediated target DNA binding
Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2022-12-08
Release date:2023-08-23
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
7VZF
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BU of 7vzf by Molmil
Cryo-EM structure of amyloid fibril formed by full-length human SOD1
Descriptor: Superoxide dismutase [Cu-Zn]
Authors:Wang, L.Q, Ma, Y.Y, Yuan, H.Y, Zhao, K, Zhang, M.Y, Wang, Q, Huang, X, Xu, W.C, Chen, J, Li, D, Zhang, D.L, Zou, L.Y, Yin, P, Liu, C, Liang, Y.
Deposit date:2021-11-16
Release date:2022-06-29
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion.
Nat Commun, 13, 2022
5J13
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BU of 5j13 by Molmil
Structural basis for TSLP antagonism by the therapeutic antibody Tezepelumab (MEDI9929 / AMG-157)
Descriptor: SULFATE ION, Thymic stromal lymphopoietin, anti-TSLP Fab-fragment, ...
Authors:Verstraete, K, Savvides, S.N.
Deposit date:2016-03-28
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Nat Commun, 8, 2017
6O1M
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BU of 6o1m by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex
Descriptor: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
Authors:Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
Deposit date:2019-02-20
Release date:2019-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
1UCW
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BU of 1ucw by Molmil
COMPLEX OF TRANSALDOLASE WITH THE REDUCED SCHIFF-BASE INTERMEDIATE
Descriptor: TRANSALDOLASE
Authors:Jia, J, Lindqvist, Y, Schneider, G.
Deposit date:1996-11-14
Release date:1997-07-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the reduced Schiff-base intermediate complex of transaldolase B from Escherichia coli: mechanistic implications for class I aldolases.
Protein Sci., 6, 1997
1S4W
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BU of 1s4w by Molmil
NMR structure of the cytoplasmic domain of integrin AIIb in DPC micelles
Descriptor: Integrin alpha-IIb
Authors:Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J.
Deposit date:2004-01-19
Release date:2004-03-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004
2VK7
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BU of 2vk7 by Molmil
THE STRUCTURE OF CLOSTRIDIUM PERFRINGENS NANI SIALIDASE AND ITS CATALYTIC INTERMEDIATES
Descriptor: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CALCIUM ION, EXO-ALPHA-SIALIDASE
Authors:Newstead, S.L, Potter, J.A, Wilson, J.C, Xu, G, Chien, C.H, Watts, A.G, Withers, S.G, Taylor, G.L.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The Structure of Clostridium Perfringens Nani Sialidase and its Catalytic Intermediates.
J.Biol.Chem., 283, 2008
3DZF
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BU of 3dzf by Molmil
Crystal structure of human CD38 extracellular domain complexed with a covalent intermediate, ara-F-ribose-5'-phosphate
Descriptor: 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
Authors:Liu, Q, Kriksunov, I.A, Jiang, H, Graeff, R, Lin, H, Lee, H.C, Hao, Q.
Deposit date:2008-07-29
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
2Y20
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BU of 2y20 by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant
Descriptor: UNCHARACTERIZED PROTEIN, ZINC ION
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-12
Release date:2011-07-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
1P8U
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BU of 1p8u by Molmil
BACTERIORHODOPSIN N' INTERMEDIATE AT 1.62 A RESOLUTION
Descriptor: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, 2,10,23-TRIMETHYL-TETRACOSANE, Bacteriorhodopsin, ...
Authors:Lanyi, J.K.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystallographic Structures of the M and N Intermediates of Bacteriorhodopsin: Assembly of a Hydrogen-Bonded Chain of Water Molecules between Asp-96 and the Retinal Schiff Base
J.Mol.Biol., 330, 2003
3EQ6
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BU of 3eq6 by Molmil
Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products
Descriptor: ADENOSINE MONOPHOSPHATE, Acyl-coenzyme A synthetase ACSM2A, Butyryl Coenzyme A
Authors:Pilka, E.S, Kochan, G, Yue, W.W, Bhatia, C, Von delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2008-09-30
Release date:2008-10-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
2Y0Q
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BU of 2y0q by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291C mutant
Descriptor: UNCHARACTERIZED PROTEIN
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-07
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
2Y0T
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BU of 2y0t by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291F mutant
Descriptor: AF1503
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-07
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
3GPC
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BU of 3gpc by Molmil
Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA
Descriptor: Acyl-coenzyme A synthetase ACSM2A, COENZYME A, MAGNESIUM ION
Authors:Pilka, E.S, Kochan, G.T, Yue, W.W, Bhatia, C, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2009-03-23
Release date:2009-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
3M26
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BU of 3m26 by Molmil
Crystallographic and Single Crystal Spectral Analysis of the Peroxidase Ferryl Intermediate
Descriptor: Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ...
Authors:Meharenna, Y.T, Poulos, T.L.
Deposit date:2010-03-06
Release date:2010-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and single-crystal spectral analysis of the peroxidase ferryl intermediate.
Biochemistry, 49, 2010
3M2I
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BU of 3m2i by Molmil
Crystallographic and Single Crystal Spectral Analysis of the Peroxidase Ferryl Intermediate
Descriptor: Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ...
Authors:Meharenna, Y.T, Poulos, T.L.
Deposit date:2010-03-07
Release date:2010-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and single-crystal spectral analysis of the peroxidase ferryl intermediate.
Biochemistry, 49, 2010
3M27
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BU of 3m27 by Molmil
Crystallographic and Single Crystal Spectral Analysis of the Peroxidase Ferryl Intermediate
Descriptor: Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ...
Authors:Meharenna, Y.T, Poulos, T.L.
Deposit date:2010-03-06
Release date:2010-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and single-crystal spectral analysis of the peroxidase ferryl intermediate.
Biochemistry, 49, 2010
3M2H
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BU of 3m2h by Molmil
Crystallographic and Single Crystal Spectral Analysis of the Peroxidase Ferryl Intermediate
Descriptor: Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ...
Authors:Meharenna, Y.T, Poulos, T.L.
Deposit date:2010-03-07
Release date:2010-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and single-crystal spectral analysis of the peroxidase ferryl intermediate.
Biochemistry, 49, 2010
4V9J
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BU of 4v9j by Molmil
70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
Deposit date:2013-04-23
Release date:2014-07-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.86 Å)
Cite:Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
7VXW
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BU of 7vxw by Molmil
Snapshots of Human PSMD10(Gankyrin) unfolding by urea: 1 hour incubation
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, UREA
Authors:Mukund Sudharsan, M.G, Dalvi, S, Venkatraman, P.
Deposit date:2021-11-13
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution.
Protein Sci., 31, 2022
7VY7
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BU of 7vy7 by Molmil
Snapshots of Human PSMD10(Gankyrin) unfolding by urea: 3 hours incubation
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, UREA
Authors:Mukund Sudharsan, M.G, Dalvi, S, Venkatraman, P.
Deposit date:2021-11-13
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution.
Protein Sci., 31, 2022
7VXV
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BU of 7vxv by Molmil
Snapshots of Human PSMD10(Gankyrin) unfolding by urea: 0 hours incubation / Native
Descriptor: 26S proteasome non-ATPase regulatory subunit 10
Authors:Mukund Sudharsan, M.G, Dalvi, S, Venkatraman, P.
Deposit date:2021-11-13
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution.
Protein Sci., 31, 2022
7VY4
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BU of 7vy4 by Molmil
Snapshots of Human PSMD10(Gankyrin) unfolding by urea: 2 hours incubation
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, UREA
Authors:Mukund Sudharsan, M.G, Dalvi, S, Venkatraman, P.
Deposit date:2021-11-13
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution.
Protein Sci., 31, 2022
4V9M
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BU of 4v9m by Molmil
70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
Deposit date:2013-04-25
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
5NJ8
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BU of 5nj8 by Molmil
Structural basis for aryl hydrocarbon receptor mediated gene activation
Descriptor: ACETATE ION, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor nuclear translocator, ...
Authors:Daumke, O, Schulte, K.W.
Deposit date:2017-03-28
Release date:2017-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
Structure, 25, 2017

223790

數據於2024-08-14公開中

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