8FFI

Structure of tetramerized MapSPARTA upon guide RNA-mediated target DNA binding

Summary for 8FFI

Entry DOI	10.2210/pdb8ffi/pdb
EMDB information	29043 29219 29222 29223 29224 29225 29226
Descriptor	TIR-APAZ, short pAgo, guide RNA, ... (5 entities in total)
Functional Keywords	pago, sparta, argonuare, oligomerization, tir domain, nad, immune system
Biological source	Maribacter polysiphoniae More
Total number of polymer chains	16
Total formula weight	502853.03
Authors	Shen, Z.F.,Yang, X.Y.,Fu, T.M. (deposition date: 2022-12-08, release date: 2023-08-23, Last modification date: 2023-09-20)
Primary citation	Shen, Z.,Yang, X.Y.,Xia, S.,Huang, W.,Taylor, D.J.,Nakanishi, K.,Fu, T.M. Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621:154-161, 2023 Cited by PubMed: 37494956 DOI: 10.1038/s41586-023-06456-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation