5Y6P
 
 | | Structure of the phycobilisome from the red alga Griffithsia pacifica | | Descriptor: | ApcD, ApcF, LC, ... | | Authors: | Zhang, J, Ma, J.F, Liu, D.S, Sun, S, Sui, S.F. | | Deposit date: | 2017-08-13 | | Release date: | 2017-11-15 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of phycobilisome from the red alga Griffithsia pacifica
Nature, 551, 2017
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3QAK
 | | Agonist bound structure of the human adenosine A2a receptor | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, Adenosine receptor A2a,lysozyme chimera | | Authors: | Xu, F, Wu, H, Katritch, V, Han, G.W, Cherezov, V, Stevens, R, GPCR Network (GPCR) | | Deposit date: | 2011-01-11 | | Release date: | 2011-03-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structure of an agonist-bound human A2A adenosine receptor.
Science, 332, 2011
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4NWR
 | | Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T33-28 | | Descriptor: | Macrophage migration inhibitory factor-like protein, integron gene cassette protein | | Authors: | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | | Deposit date: | 2013-12-06 | | Release date: | 2014-05-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
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8J07
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3P3N
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8IKA
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8OH6
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (500umol) | | Descriptor: | 18S, 25S (gene name XR_002086444.1), 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | | Deposit date: | 2023-03-20 | | Release date: | 2024-10-02 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8OEQ
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (250uM) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | | Deposit date: | 2023-03-12 | | Release date: | 2024-09-25 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8OJ3
 | | Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418 (rotated state) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | | Deposit date: | 2023-03-23 | | Release date: | 2024-10-09 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8PHU
 | | Asymmetric structure of the portal-containing cap of the Borrelia bacteriophage BB1 procapsid | | Descriptor: | Decorator protein P03, Decorator protein P04, Decorator protein P05, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-20 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (7.41 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
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4OAR
 | | Progesterone receptor with bound ulipristal acetate and a peptide from the co-repressor SMRT | | Descriptor: | Peptide from Nuclear receptor corepressor 2, Progesterone receptor, [(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopen ta[a]phenanthren-17-yl] acetate | | Authors: | Petit-Topin, I, Fay, M.R, Resche-Rigon, M, Ulmann, A, Gainer, E, Rafestin-Oblin, M.-E, Fagart, J. | | Deposit date: | 2014-01-06 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors.
J.Steroid Biochem.Mol.Biol., 144PB, 2014
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3P3P
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3SH4
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3SJO
 | | structure of EV71 3C in complex with Rupintrivir (AG7088) | | Descriptor: | 3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | Authors: | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | Deposit date: | 2011-06-21 | | Release date: | 2011-08-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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3SAN
 | | Crystal structure of influenza A virus neuraminidase N5 complexed with Zanamivir | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. | | Deposit date: | 2011-06-03 | | Release date: | 2011-08-10 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
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3SH5
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3SL7
 | | Crystal structure of CBS-pair protein, CBSX2 from Arabidopsis thaliana | | Descriptor: | ACETATE ION, CBS domain-containing protein CBSX2, GLYCEROL | | Authors: | Jeong, B.-C, Lee, M.-R, Song, H.K. | | Deposit date: | 2011-06-24 | | Release date: | 2011-11-09 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.905 Å) | | Cite: | Single cystathionine beta-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis
Plant Cell, 23, 2011
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3SAL
 | | Crystal Structure of Influenza A Virus Neuraminidase N5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | Authors: | Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. | | Deposit date: | 2011-06-03 | | Release date: | 2011-08-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
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5JKD
 | | Crystal structure of human IZUMO1-JUNO complex (crystal form 2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ... | | Authors: | Ohto, U, Ishida, H, Shimizu, T. | | Deposit date: | 2016-04-26 | | Release date: | 2016-06-22 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
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4U25
 | | Crystal structure of the E. coli ribosome bound to virginiamycin M1. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | Deposit date: | 2014-07-16 | | Release date: | 2014-07-30 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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5JKE
 | | Crystal structure of human IZUMO1-JUNO complex (crystal form 3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ... | | Authors: | Ohto, U, Ishida, H, Shimizu, T. | | Deposit date: | 2016-04-26 | | Release date: | 2016-06-22 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
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5JKB
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5JKA
 | | Crystal structure of human JUNO (crystal form 1) | | Descriptor: | CHLORIDE ION, Sperm-egg fusion protein Juno, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Ohto, U, Ishida, H, Shimizu, T. | | Deposit date: | 2016-04-26 | | Release date: | 2016-06-22 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
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4U1V
 | | Crystal structure of the E. coli ribosome bound to linopristin. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | Deposit date: | 2014-07-16 | | Release date: | 2014-07-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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5JVG
 | | The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ... | | Authors: | Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | Deposit date: | 2016-05-11 | | Release date: | 2016-11-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.428 Å) | | Cite: | Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
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