5JVG

The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin

Summary for 5JVG

Entry DOI	10.2210/pdb5jvg/pdb
Descriptor	23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (33 entities in total)
Functional Keywords	deinococcus radiodurans, avilamycin, degradable antibiotics, ribosome, large ribosomal subunit, resistance
Biological source	Deinococcus radiodurans R1 More
Total number of polymer chains	29
Total formula weight	1372760.85
Authors	Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. (deposition date: 2016-05-11, release date: 2016-11-09, Last modification date: 2024-01-10)
Primary citation	Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding. Proc.Natl.Acad.Sci.USA, 113:E6796-E6805, 2016 Cited by PubMed: 27791159 DOI: 10.1073/pnas.1614297113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.428 Å)

Structure validation