8OJ3

Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418 (rotated state)

This is a non-PDB format compatible entry.

Summary for 8OJ3

• Entry DOI: 10.2210/pdb8oj3/pdb
• Descriptor: 25S ribosomal RNA, 60S ribosomal protein L8, 60S ribosomal protein L9-B, ... (86 entities in total)
• Functional Keywords: candida albicans, ribosome, geneticin, g418, mefloquine, ptc read-through
• Biological source: Candida albicans; More
• Total number of polymer chains: 160
• Total formula weight: 6320134.89

Authors

Kolosova, O.,Zgadzay, Y.,Yusupov, M. (deposition date: 2023-03-23, release date: 2024-10-09, Last modification date: 2025-04-30)

• Primary citation: Kolosova, O.,Zgadzay, Y.,Yusupov, M.; Mechanism of read-through enhancement by aminoglycosides and mefloquine; Proc.Natl.Acad.Sci.USA, 2025; DOI: 10.1073/pnas.2420261122

Experimental method

X-RAY DIFFRACTION (3.5 Å)