6WIW
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![BU of 6wiw by Molmil](/molmil-images/mine/6wiw) | c-Src Bound to ATP-Competitive Inhibitor I14 | Descriptor: | N-(3-{[4-amino-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl}-4-methylphenyl)acetamide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Vilas-Boas, J, Thakur, M.K, Fang, L, Maly, D, Seeliger, M.A. | Deposit date: | 2020-04-10 | Release date: | 2020-06-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture. Acs Chem.Biol., 15, 2020
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4Z8K
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4Q70
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![BU of 4q70 by Molmil](/molmil-images/mine/4q70) | Light Harvesting Protein Phycocyanin in high resolution using a femtosecond X-Ray laser | Descriptor: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN | Authors: | Fromme, R, Roy-Chowdhury, S, Basu, S, Yoon, C, Fromme, P. | Deposit date: | 2014-04-23 | Release date: | 2015-05-06 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Observations on the Light Harvesting Protein Phycocyanin structure in high resolution using a femtosecond X-Ray laser TO BE PUBLISHED
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7FDW
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![BU of 7fdw by Molmil](/molmil-images/mine/7fdw) | Crystal structure of pepsin cleaved lactoferrin C-lobe at 2.28 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Singh, P.K, Singh, J, Maurya, A, Sharma, P, Sharma, S, Singh, T.P. | Deposit date: | 2021-07-18 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.277 Å) | Cite: | A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 angstrom Resolution. Protein J., 40, 2021
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7EXB
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![BU of 7exb by Molmil](/molmil-images/mine/7exb) | DfgA-DfgB complex apo 2.4 angstrom | Descriptor: | DfgB, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Mori, T, Senda, M, Senda, T, Abe, I. | Deposit date: | 2021-05-26 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes. Nat Commun, 12, 2021
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6G13
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![BU of 6g13 by Molmil](/molmil-images/mine/6g13) | C-terminal domain of MERS-CoV nucleocapsid | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Nucleoprotein, ... | Authors: | Nguyen, T.H.V, Ferron, F.P, Lichiere, J, Canard, B, Papageorgiou, N, Coutard, B. | Deposit date: | 2018-03-20 | Release date: | 2019-02-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein. Acta Crystallogr D Struct Biol, 75, 2019
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6SK3
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![BU of 6sk3 by Molmil](/molmil-images/mine/6sk3) | C-terminal HsNMT1 deltaC3 truncation in complex with both MyrCoA and GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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7R1Z
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8PX2
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8PX8
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4ZES
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![BU of 4zes by Molmil](/molmil-images/mine/4zes) | Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside | Descriptor: | C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E. | Deposit date: | 2015-04-20 | Release date: | 2015-05-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2. J.Biol.Chem., 290, 2015
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6EF8
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![BU of 6ef8 by Molmil](/molmil-images/mine/6ef8) | Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens | Descriptor: | C-type cytochrome OmcS, HEME C | Authors: | Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S. | Deposit date: | 2018-08-16 | Release date: | 2019-04-10 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers. Cell, 177, 2019
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1OPJ
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![BU of 1opj by Molmil](/molmil-images/mine/1opj) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, MYRISTIC ACID, ... | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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6SWP
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![BU of 6swp by Molmil](/molmil-images/mine/6swp) | C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH iBET-BD2 (GSK046) | Descriptor: | 1,2-ETHANEDIOL, 4-acetamido-3-fluoranyl-~{N}-(4-oxidanylcyclohexyl)-5-[(1~{S})-1-phenylethoxy]benzamide, Bromodomain-containing protein 2 | Authors: | Chung, C. | Deposit date: | 2019-09-22 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science, 368, 2020
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7XA3
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![BU of 7xa3 by Molmil](/molmil-images/mine/7xa3) | Cryo-EM structure of the CCL2 bound CCR2-Gi complex | Descriptor: | C-C motif chemokine 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H. | Deposit date: | 2022-03-17 | Release date: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discov, 8, 2022
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7X9Y
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![BU of 7x9y by Molmil](/molmil-images/mine/7x9y) | Cryo-EM structure of the apo CCR3-Gi complex | Descriptor: | C-C chemokine receptor type 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H. | Deposit date: | 2022-03-16 | Release date: | 2022-08-24 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discov, 8, 2022
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7VLA
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![BU of 7vla by Molmil](/molmil-images/mine/7vla) | Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex | Descriptor: | C-C chemokine receptor type 1, CCL15(27-92), CHOLESTEROL, ... | Authors: | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | Deposit date: | 2021-10-02 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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7VL8
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![BU of 7vl8 by Molmil](/molmil-images/mine/7vl8) | Cryo-EM structure of the Apo CCR1-Gi complex | Descriptor: | C-C chemokine receptor type 1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | Deposit date: | 2021-10-02 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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5EKI
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7VL9
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![BU of 7vl9 by Molmil](/molmil-images/mine/7vl9) | Cryo-EM structure of the CCL15(26-92) bound CCR1-Gi complex | Descriptor: | C-C chemokine receptor type 1, CCL15(26-92), CHOLESTEROL, ... | Authors: | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | Deposit date: | 2021-10-02 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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4ZET
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![BU of 4zet by Molmil](/molmil-images/mine/4zet) | Blood dendritic cell antigen 2 (BDCA-2) complexed with GalGlcNAcMan | Descriptor: | C-type lectin domain family 4 member C, CALCIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | Authors: | Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E. | Deposit date: | 2015-04-20 | Release date: | 2015-05-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2. J.Biol.Chem., 290, 2015
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8R3F
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![BU of 8r3f by Molmil](/molmil-images/mine/8r3f) | C-terminal Rel-homology Domain of NFAT1 | Descriptor: | (4~{S})-6-fluoranyl-3,4-dihydro-2~{H}-chromen-4-amine, Nuclear factor of activated T-cells, cytoplasmic 2 | Authors: | Zak, K.M, Boettcher, J. | Deposit date: | 2023-11-08 | Release date: | 2024-03-06 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Ligandability assessment of the C-terminal Rel-homology domain of NFAT1. Arch Pharm, 357, 2024
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1OPK
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![BU of 1opk by Molmil](/molmil-images/mine/1opk) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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1OPL
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![BU of 1opl by Molmil](/molmil-images/mine/1opl) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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8XBS
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![BU of 8xbs by Molmil](/molmil-images/mine/8xbs) | C. elegans apo-SID1 structure | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gong, D.S. | Deposit date: | 2023-12-07 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Structural basis for double-stranded RNA recognition by SID1. Nucleic Acids Res., 52, 2024
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