Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8OWT
DownloadVisualize
BU of 8owt by Molmil
SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A8, ...
Authors:Mikolajek, H, Naismith, J.H, Owens, R.J.
Deposit date:2023-04-28
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OWW
DownloadVisualize
BU of 8oww by Molmil
B5-5 nanobody bound to SARS-CoV-2 spike RBD (Wuhan)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, B5-5 nanobody, ...
Authors:Cornish, K.A.S, Naismith, J.H, Owens, R.J.
Deposit date:2023-04-28
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OWV
DownloadVisualize
BU of 8owv by Molmil
H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F2, GLYCEROL, ...
Authors:Mikolajek, H, Naismith, J.H, Owens, R.J.
Deposit date:2023-04-28
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
7GQT
DownloadVisualize
BU of 7gqt by Molmil
Crystal Structure of Werner helicase fragment 517-945 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, MAGNESIUM ION, ...
Authors:Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
Deposit date:2023-10-19
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
7GQU
DownloadVisualize
BU of 7gqu by Molmil
Crystal Structure of Werner helicase fragment 517-945 in covalent complex with N-[(E,1S)-1-cyclopropyl-3-methylsulfonylprop-2-enyl]-2-(1,1-difluoroethyl)-4-phenoxypyrimidine-5-carboxamide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, GLYCEROL, ...
Authors:Classen, M, Benz, J, Brugger, D, Tagliente, O, Rudolph, M.G.
Deposit date:2023-10-19
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
7GQS
DownloadVisualize
BU of 7gqs by Molmil
Crystal Structure of Werner helicase fragment 517-945 in complex with ADP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, ...
Authors:Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
Deposit date:2023-10-19
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
9EN6
DownloadVisualize
BU of 9en6 by Molmil
Crystal structure of RNA G2C4 repeats - native model pH 6.5
Descriptor: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Mateja-Pluta, M, Kiliszek, A.
Deposit date:2024-03-12
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (0.918 Å)
Cite:Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.
Nucleic Acids Res., 2024
8JZM
DownloadVisualize
BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
Descriptor: Toll/interleukin-1 receptor domain-containing adapter protein
Authors:Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
Deposit date:2023-07-05
Release date:2024-05-01
Method:SOLUTION NMR
Cite:o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
8JYW
DownloadVisualize
BU of 8jyw by Molmil
Cryo-EM structure of the gasdermin pore from Trichoplax adhaerens
Descriptor: Gasdermin pore forming domain-containing protein
Authors:Hou, Y.J, Sun, Q, Zeng, H, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYV
DownloadVisualize
BU of 8jyv by Molmil
Crystal structure of the gasdermin from Trichoplax adhaerens
Descriptor: Gasdermin pore forming domain-containing protein
Authors:Zeng, H, Hou, Y.J, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYY
DownloadVisualize
BU of 8jyy by Molmil
Crystal structure of the gasdermin-like protein RCD-1-2 from Neurospora crassa
Descriptor: RCD-1-2
Authors:Li, Y, Hou, Y.J, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYZ
DownloadVisualize
BU of 8jyz by Molmil
Cryo-EM structure of RCD-1 pore from Neurospora crassa
Descriptor: Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2
Authors:Hou, Y.J, Sun, Q, Li, Y, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8QMH
DownloadVisualize
BU of 8qmh by Molmil
Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77
Descriptor: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Kiliszek, A, Ryczek, M, Blaszczyk, L.
Deposit date:2023-09-22
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.
Nucleic Acids Res., 2024
8QMI
DownloadVisualize
BU of 8qmi by Molmil
Crystal structure of RNA G2C4 repeats - native model
Descriptor: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Blaszczyk, L, Kiliszek, A.
Deposit date:2023-09-22
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.
Nucleic Acids Res., 2024
8XI6
DownloadVisualize
BU of 8xi6 by Molmil
SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ishimaru, H, Nishimura, M, Shigematsu, H, Marini, M.I, Hasegawa, N, Takamiya, R, Iwata, S, Mori, Y.
Deposit date:2023-12-19
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein.
J.Virol., 98, 2024
8OT7
DownloadVisualize
BU of 8ot7 by Molmil
Crystal structure of an 8-repeat consensus TPR superhelix with Barium
Descriptor: BARIUM ION, Consensus tetratricopeptide repeat protein
Authors:Liutkus, M, Rojas, A.L, Cortajarena, A.L.
Deposit date:2023-04-20
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
8OJ2
DownloadVisualize
BU of 8oj2 by Molmil
Crystal structure of the DNA binding domain of M. polymorpha Auxin Response Factor 2 (MpARF2) in complex with protomor-like sequence IR7
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Auxin response factor, CHLORIDE ION, ...
Authors:Crespo, I, Weijers, D, Boer, D.R.
Deposit date:2023-03-23
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of the DNA binding domain of M. polymorpha Auxin Response Factor 2 (MpARF2) in complex with protomor-like sequence IR7
To Be Published
8U6Y
DownloadVisualize
BU of 8u6y by Molmil
Preholo-Proteasome from Beta 3 D205 deletion
Descriptor: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
Authors:Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J.
Deposit date:2023-09-14
Release date:2024-04-17
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of autocatalytic activation during proteasome assembly.
Nat.Struct.Mol.Biol., 2024
8U7U
DownloadVisualize
BU of 8u7u by Molmil
Proteasome 20S Core Particle from Beta 3 D205 deletion
Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J.
Deposit date:2023-09-15
Release date:2024-04-17
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.16 Å)
Cite:Mechanism of autocatalytic activation during proteasome assembly.
Nat.Struct.Mol.Biol., 2024
8W22
DownloadVisualize
BU of 8w22 by Molmil
Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1)
Descriptor: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
Authors:Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
Deposit date:2024-02-19
Release date:2024-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8W20
DownloadVisualize
BU of 8w20 by Molmil
Umb1 umbrella toxin particle
Descriptor: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
Authors:Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
Deposit date:2024-02-19
Release date:2024-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8TXA
DownloadVisualize
BU of 8txa by Molmil
Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum
Descriptor: tRNA (guanine-N(1)-)-methyltransferase
Authors:Balsamo, A, Bruno, C, Edele, C, Fabian, T, Jannotta, R, Lee, R, Schryver, D, Warsaw, J, Warsaw, L, Stojanoff, V, Battaile, K, Perez, A, Bolen, R.
Deposit date:2023-08-23
Release date:2024-04-10
Method:X-RAY DIFFRACTION (1.591 Å)
Cite:Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum
To Be Published
8IY7
DownloadVisualize
BU of 8iy7 by Molmil
Cryo-EM structure of DIP-2I8I fibril polymorph1
Descriptor: GLY-PHI-GLY-ASN-GLY-ASN-GLY-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-04-04
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cryo-EM structure of DIP-2I8I fibril polymorph1
To Be Published
8IZZ
DownloadVisualize
BU of 8izz by Molmil
Cryo-EM structure of DIP-2I8I polymorph 2
Descriptor: GLY-PHI-GLY-ASN-GLY-ASN-GLY-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-04-09
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structure of DIP-2I8I fibril polymorph 2
To Be Published
8JBW
DownloadVisualize
BU of 8jbw by Molmil
Crystal structure of ZtHPPD-(+)-Usnic acid complex
Descriptor: (9bR)-2,6-diethanoyl-8,9b-dimethyl-3,7,9-tris(oxidanyl)dibenzofuran-1-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
Authors:Lin, H.-Y, Dong, J, Yang, G.-F.
Deposit date:2023-05-09
Release date:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and Development of 4-Hydroxyphenylpyruvate Dioxygenase as a Novel Crop Fungicide Target.
J.Agric.Food Chem., 71, 2023

221716

數據於2024-06-26公開中

PDB statisticsPDBj update infoContact PDBjnumon