8OWT

SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound

This is a non-PDB format compatible entry.

Summary for 8OWT

• Entry DOI: 10.2210/pdb8owt/pdb
• Descriptor: Nanobody A8, Spike protein S1, Nanobody H3, ... (6 entities in total)
• Functional Keywords: nanobody, complex, receptor binding domain, sars-cov-2, viral protein
• Biological source: Lama glama; More
• Total number of polymer chains: 6
• Total formula weight: 107302.55

Authors

Mikolajek, H.,Naismith, J.H.,Owens, R.J. (deposition date: 2023-04-28, release date: 2024-05-08, Last modification date: 2024-06-19)

• Primary citation: Cornish, K.,Huo, J.,Jones, L.,Sharma, P.,Thrush, J.W.,Abdelkarim, S.,Kipar, A.,Ramadurai, S.,Weckener, M.,Mikolajek, H.,Liu, S.,Buckle, I.,Bentley, E.,Kirby, A.,Han, X.,Laidlaw, S.M.,Hill, M.,Eyssen, L.,Norman, C.,Le Bas, A.,Clarke, J.,James, W.,Stewart, J.P.,Carroll, M.,Naismith, J.H.,Owens, R.J.; Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.; Open Biology, 14:230252-230252, 2024; PubMed: 38835241; DOI: 10.1098/rsob.230252

Experimental method

X-RAY DIFFRACTION (2.37 Å)