8OWT

SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (AAA, DDD)	Nanobody A8	polymer	132	14481.0	2		Lama glama
2	B, E (BBB, EEE)	Spike protein S1	polymer	210	23716.6	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
3	C, F (CCC, FFF)	Nanobody H3	polymer	136	15134.8	2		Lama glama
4	G, H (BBB, EEE)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	I (EEE)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
6	J, K, L, M, N... (AAA, BBB, CCC, DDD, EEE...)	water	water		18.0	172	Chemie (HOH)

Sequence modifications

BBB, EEE: 330 - 532 (UniProt: P0DTC2)

PDB	External Database	Details
Lys 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	106664.9
Non-Polymers*	Number of molecules	3
	Total formula weight	637.7
All*	Total formula weight	107302.6

*Water molecules are not included.