9EN6

Crystal structure of RNA G2C4 repeats - native model pH 6.5

This is a non-PDB format compatible entry.

Summary for 9EN6

• Entry DOI: 10.2210/pdb9en6/pdb
• Related: 8QMH 8QMI
• Descriptor: RNA (5'-R(*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION (3 entities in total)
• Functional Keywords: rna, g2c4 repeats, als, ftd, hexanucleotide repeats
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 7537.64

Authors

Mateja-Pluta, M.,Kiliszek, A. (deposition date: 2024-03-12, release date: 2024-05-01, Last modification date: 2024-07-03)

• Primary citation: Blaszczyk, L.,Ryczek, M.,Das, B.,Mateja-Pluta, M.,Bejger, M.,Sliwiak, J.,Nakatani, K.,Kiliszek, A.; Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.; Nucleic Acids Res., 52:6707-6717, 2024; PubMed: 38738637; DOI: 10.1093/nar/gkae376

Experimental method

X-RAY DIFFRACTION (0.918 Å)