4N8P
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![BU of 4n8p by Molmil](/molmil-images/mine/4n8p) | Crystal structure of a strand swapped CTLA-4 from Duckbill Platypus [PSI-NYSGRC-012711] | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Uncharacterized protein | Authors: | Kumar, P.R, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2013-10-17 | Release date: | 2013-10-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Crystal structure of a strand swapped CTLA-4 from Duckbill Platypus [PSI-NYSGRC-012711] to be published
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4NFB
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![BU of 4nfb by Molmil](/molmil-images/mine/4nfb) | Structure of paired immunoglobulin-like type 2 receptor (PILR ) | Descriptor: | Paired immunoglobulin-like type 2 receptor alpha | Authors: | Lu, Q, Lu, G, Qi, J, Li, Y, Zhang, Y, Wang, H, Fan, Z, Yan, J, Gao, G. | Deposit date: | 2013-10-31 | Release date: | 2014-05-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid Proc.Natl.Acad.Sci.USA, 111, 2014
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6D48
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![BU of 6d48 by Molmil](/molmil-images/mine/6d48) | Cell Surface Receptor | Descriptor: | Myeloid cell surface antigen CD33 | Authors: | Hermans, S.J, Miles, L.A, Parker, M.W. | Deposit date: | 2018-04-17 | Release date: | 2019-04-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.776 Å) | Cite: | Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis. Iscience, 19, 2019
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4MZ2
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![BU of 4mz2 by Molmil](/molmil-images/mine/4mz2) | |
4NOB
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![BU of 4nob by Molmil](/molmil-images/mine/4nob) | Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220] | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | Authors: | Kumar, P.R, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2013-11-19 | Release date: | 2013-12-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor to be published
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1MVU
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![BU of 1mvu by Molmil](/molmil-images/mine/1mvu) | |
1NCN
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![BU of 1ncn by Molmil](/molmil-images/mine/1ncn) | |
1NKO
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![BU of 1nko by Molmil](/molmil-images/mine/1nko) | Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7 | Descriptor: | Sialic acid binding Ig-like lectin 7 | Authors: | Dimasi, N, Attril, H, van Aalten, D.M.F, Moretta, L, Biassoni, R, Mariuzza, R.A. | Deposit date: | 2003-01-03 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1. Acta Crystallogr.,Sect.D, 60, 2004
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1NEU
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![BU of 1neu by Molmil](/molmil-images/mine/1neu) | STRUCTURE OF MYELIN MEMBRANE ADHESION MOLECULE P0 | Descriptor: | MYELIN P0 PROTEIN | Authors: | Shapiro, L, Doyle, J.P, Hensley, P, Colman, D.R, Hendrickson, W.A. | Deposit date: | 1996-09-24 | Release date: | 1997-05-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron, 17, 1996
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1OHQ
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![BU of 1ohq by Molmil](/molmil-images/mine/1ohq) | Crystal structure of HEL4, a soluble human VH antibody domain resistant to aggregation | Descriptor: | IMMUNOGLOBULIN | Authors: | Jespers, L, Schon, O, James, L.C, Veprintsev, D, Winter, G. | Deposit date: | 2003-05-30 | Release date: | 2004-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Hel4, a Soluble, Refoldable Human V(H) Single Domain with a Germ-Line Scaffold J.Mol.Biol., 337, 2004
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1P4B
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![BU of 1p4b by Molmil](/molmil-images/mine/1p4b) | Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P). | Descriptor: | Antibody Variable heavy chain, Antibody Variable light chain, GCN4(7P-14P) peptide | Authors: | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | Deposit date: | 2003-04-22 | Release date: | 2004-05-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity. J.Biol.Chem., 279, 2004
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1P4I
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![BU of 1p4i by Molmil](/molmil-images/mine/1p4i) | Crystal Structure of scFv against peptide GCN4 | Descriptor: | ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain | Authors: | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | Deposit date: | 2003-04-23 | Release date: | 2004-05-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity. J.Biol.Chem., 279, 2004
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1PEW
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![BU of 1pew by Molmil](/molmil-images/mine/1pew) | High Resolution Crystal Structure of Jto2, a mutant of the non-amyloidogenic Lamba6 Light Chain, Jto | Descriptor: | CADMIUM ION, Jto2, a LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN, ... | Authors: | Dealwis, C, Gupta, V, Wilkerson, M. | Deposit date: | 2003-05-22 | Release date: | 2004-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four V(lambda)6 proteins J.Mol.Recog., 17, 2004
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1PKQ
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![BU of 1pkq by Molmil](/molmil-images/mine/1pkq) | Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex | Descriptor: | (8-18C5) chimeric Fab, heavy chain, light chain, ... | Authors: | Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2003-06-06 | Release date: | 2003-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein Proc.Natl.Acad.Sci.USA, 100, 2003
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1NGW
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![BU of 1ngw by Molmil](/molmil-images/mine/1ngw) | Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin | Descriptor: | Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ... | Authors: | Yin, J, Andryski, S.E, Beuscher IV, A.E, Stevens, R.C, Schultz, P.G. | Deposit date: | 2002-12-18 | Release date: | 2003-02-04 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural evidence for substrate strain in antibody catalysis Proc.Natl.Acad.Sci.USA, 100, 2003
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1O7V
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![BU of 1o7v by Molmil](/molmil-images/mine/1o7v) | High resolution structure of Siglec-7 | Descriptor: | SIALIC ACID BINDING IG-LIKE LECTIN 7, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Alphey, M.S, Attrill, H, Crocker, P.R, Van Aalten, D.M.F. | Deposit date: | 2002-11-14 | Release date: | 2003-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family. J.Biol.Chem., 278, 2003
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1OD7
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![BU of 1od7 by Molmil](/molmil-images/mine/1od7) | N-terminal of Sialoadhesin in complex with Me-a-9-N-(naphthyl-2-carbonyl)-amino-9-deoxy-Neu5Ac (NAP compound) | Descriptor: | ME-A-9-N-(NAPHTHYL-2-CARBONYL)-AMINO-9-DEOXY-NEU5AC, SIALOADHESIN | Authors: | Zaccai, N.R, Maenaka, K, Maenaka, T, Crocker, P.R, Brossmer, R, Kelm, S, Jones, E.Y. | Deposit date: | 2003-02-14 | Release date: | 2003-05-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin Structure, 11, 2003
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1Q0X
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![BU of 1q0x by Molmil](/molmil-images/mine/1q0x) | Anti-morphine Antibody 9B1 Unliganded Form | Descriptor: | Fab 9B1, heavy chain, light chain, ... | Authors: | Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D. | Deposit date: | 2003-07-17 | Release date: | 2004-04-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine J.Mol.Biol., 337, 2004
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1OCW
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1PKO
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![BU of 1pko by Molmil](/molmil-images/mine/1pko) | Myelin Oligodendrocyte Glycoprotein (MOG) | Descriptor: | Myelin Oligodendrocyte Glycoprotein | Authors: | Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2003-06-06 | Release date: | 2003-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein Proc.Natl.Acad.Sci.USA, 100, 2003
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1O7S
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![BU of 1o7s by Molmil](/molmil-images/mine/1o7s) | High resolution structure of Siglec-7 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, ... | Authors: | Alphey, M.S, Attrill, H, Crocker, P.R, Van Aalten, D.M.F. | Deposit date: | 2002-11-12 | Release date: | 2003-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | High Resolution Structures of Siglec-7 - Insights Into Ligand Specificity in the Siglec Family J.Biol.Chem., 278, 2003
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1NPU
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![BU of 1npu by Molmil](/molmil-images/mine/1npu) | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1 | Descriptor: | Programmed cell death protein 1 | Authors: | Zhang, X, Schwartz, J.-C.D, Guo, X, Cao, E, Chen, L, Zhang, Z.-Y, Nathenson, S.G, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-01-20 | Release date: | 2004-03-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity, 20, 2004
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1OAU
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![BU of 1oau by Molmil](/molmil-images/mine/1oau) | Fv Structure of the IgE SPE-7 in complex with DNP-Ser (immunising hapten) | Descriptor: | 2,4-DINITROPHENOL, IMIDAZOLE, IMMUNOGLOBULIN E, ... | Authors: | James, L.C, Roversi, P, Tawfik, D. | Deposit date: | 2003-01-21 | Release date: | 2004-01-15 | Last modified: | 2013-10-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Antibody Multispecificity Mediated by Conformational Diversity Science, 299, 2003
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1ODA
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![BU of 1oda by Molmil](/molmil-images/mine/1oda) | N-terminal of Sialoadhesin in complex with Me-a-9-N-(biphenyl-4-carbonyl)-amino-9-deoxy-Neu5Ac (BIP compound) | Descriptor: | ME-A-9-N-(BIPHENYL-4-CARBONYL)-AMINO-9-DEOXY-NEU5AC, SIALOADHESIN | Authors: | Zaccai, N.R, Maenaka, K, Maenaka, T, Crocker, P.R, Brossmer, R, Kelm, S, Jones, E.Y. | Deposit date: | 2003-02-14 | Release date: | 2003-08-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structure Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin Structure, 11, 2003
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1OAY
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![BU of 1oay by Molmil](/molmil-images/mine/1oay) | |