5T2A
 
 | | CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution | | Descriptor: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Zhang, X, Lai, M, Zhou, Z.H. | | Deposit date: | 2016-08-23 | | Release date: | 2017-01-25 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
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1TFW
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2YKA
 | | RRM domain of mRNA export adaptor REF2-I bound to HVS ORF57 peptide | | Descriptor: | 52 KDA IMMEDIATE-EARLY PHOSPHOPROTEIN, RNA AND EXPORT FACTOR-BINDING PROTEIN 2 | | Authors: | Tunnicliffe, R.B, Hautbergue, G.M, Kalra, P, Wilson, S.A, Golovanov, A.P. | | Deposit date: | 2011-05-26 | | Release date: | 2012-06-13 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri Orf57 to the Mammalian Export Adaptor Alyref.
Plos Pathog., 10, 2014
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8XC1
 | | C. elegans SID1 in complex with dsRNA | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Gong, D.S. | | Deposit date: | 2023-12-07 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.21 Å) | | Cite: | Structural basis for double-stranded RNA recognition by SID1.
Nucleic Acids Res., 52, 2024
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6Y3Z
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5M73
 | | Structure of the human SRP S domain with SRP72 RNA-binding domain | | Descriptor: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | | Deposit date: | 2016-10-26 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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7S0S
 | | M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit | | Descriptor: | 16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA, 23S rRNA, 50S ribosomal protein L10, ... | | Authors: | Laughlin, Z.T, Dunham, C.M, Conn, G.L. | | Deposit date: | 2021-08-31 | | Release date: | 2022-03-30 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7BZF
 | | COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex | | Descriptor: | Non-structural protein 7, Non-structural protein 8, RNA (31-MER), ... | | Authors: | Wang, Q, Gao, Y, Ji, W, Mu, A, Rao, Z. | | Deposit date: | 2020-04-27 | | Release date: | 2020-06-03 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Cell, 182, 2020
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6VFF
 | | Dimer of Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence derived from human GLI1 gene | | Descriptor: | Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5-R(*GP*CP*UP*CP*GP*CP*GP*AP*UP*GP*CP*UP*(8AZ)P*GP*AP*GP*GP*GP*CP* UP*CP*UP*GP*AP*UP*AP*GP*CP*UP*AP*CP*G)-3), ... | | Authors: | Thuy-boun, A.S, Fisher, A.J, Beal, P.A. | | Deposit date: | 2020-01-03 | | Release date: | 2020-07-01 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition.
Nucleic Acids Res., 48, 2020
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6BSJ
 | | Structure of HIV-1 RT complexed with an RNA/DNA hybrid sequence non-preferred for RNA hydrolysis | | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, CALCIUM ION, DNA (5'-D(*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP*TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3'), ... | | Authors: | Tian, L, Kim, M, Yang, W. | | Deposit date: | 2017-12-03 | | Release date: | 2018-01-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BSI
 | | Structure of HIV-1 RT complexed with an RNA/DNA hybrid containing the polypurine-tract sequence | | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, CALCIUM ION, DNA (5'-D(*GP*TP*TP*TP*TP*TP*CP*TP*TP*TP*TP*GP*TP*TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3'), ... | | Authors: | Tian, L, Kim, M, Yang, W. | | Deposit date: | 2017-12-03 | | Release date: | 2018-01-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BSH
 | | Structure of HIV-1 RT complexed with RNA/DNA hybrid in the RNA hydrolysis mode | | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, CALCIUM ION, DNA (5'-D(*GP*TP*AP*TP*GP*CP*CP*AP*CP*TP*AP*GP*TP*TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3'), ... | | Authors: | Tian, L, Kim, M, Yang, W. | | Deposit date: | 2017-12-03 | | Release date: | 2018-01-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.649 Å) | | Cite: | Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4ED5
 | | Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | | Descriptor: | 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ... | | Authors: | Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X. | | Deposit date: | 2012-03-27 | | Release date: | 2012-05-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
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5FSW
 | | RNA dependent RNA polymerase QDE-1 from Thielavia terrestris | | Descriptor: | RNA DEPENDENT RNA POLYMERASE QDE-1 | | Authors: | Qian, X, Hamid, F.M, El Sahili, A, Darwis, D.A, Wong, Y.H, Bhushan, S, Makeyev, E.V, Lescar, J. | | Deposit date: | 2016-01-08 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Functional Evolution in Orthologous Cell-Encoded RNA-Dependent RNA Polymerases
J.Biol.Chem., 291, 2016
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5UDJ
 | | IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDI
 | | IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap) | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDL
 | | IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap) | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6NUE
 | | Small conformation of apo CRISPR_Csm complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | Authors: | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | Deposit date: | 2019-01-31 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
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6TY8
 | | In situ structure of BmCPV RNA dependent RNA polymerase at quiescent state | | Descriptor: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-dependent RNA Polymerase, Viral structural protein 4 | | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | Deposit date: | 2019-08-08 | | Release date: | 2019-11-20 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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5UDK
 | | IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7UU3
 | | Crystal structure of APOBEC3G complex with 3'overhangs RNA-Complex | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(*CP*CP*CP*AP*CP*GP*GP*GP*AP*AP*U)-3'), RNA (5'-R(*CP*CP*CP*GP*UP*GP*GP*GP*AP*AP*U)-3'), ... | | Authors: | Yang, H, Li, S, Chen, X.S. | | Deposit date: | 2022-04-28 | | Release date: | 2023-01-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.099 Å) | | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G.
Nat Commun, 13, 2022
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7MKO
 | | Escherichia coli RNA polymerase elongation complex | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Qayyum, M.Z, Murakami, K.S. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-02 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli.
J.Biol.Chem., 297, 2021
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7MKN
 | | Escherichia coli RNA polymerase and RapA elongation complex | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Qayyum, M.Z, Murakami, K.S. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-02 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli.
J.Biol.Chem., 297, 2021
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3ULD
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4NZ6
 | | Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p): RNA binding, activity, and atomic model | | Descriptor: | 1,2-ETHANEDIOL, D-GLUTAMIC ACID, D-LYSINE, ... | | Authors: | Huet, T, Thore, S. | | Deposit date: | 2013-12-11 | | Release date: | 2014-05-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model
Plos One, 9, 2014
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