5UDL
IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap)
Summary for 5UDL
Entry DOI | 10.2210/pdb5udl/pdb |
Related | 5udi 5udj 5udk |
Descriptor | Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), TRIETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | mrna cap, n7-methylguanosine-triphosphate rna, tetratricopeptide repeat, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 57463.72 |
Authors | Abbas, Y.M.,Martinez-Montero, S.,Damha, M.J.,Nagar, B. (deposition date: 2016-12-27, release date: 2017-03-01, Last modification date: 2024-03-06) |
Primary citation | Abbas, Y.M.,Laudenbach, B.T.,Martinez-Montero, S.,Cencic, R.,Habjan, M.,Pichlmair, A.,Damha, M.J.,Pelletier, J.,Nagar, B. Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114:E2106-E2115, 2017 Cited by PubMed: 28251928DOI: 10.1073/pnas.1612444114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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