5UDL
IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced protein with tetratricopeptide repeats 1 | polymer | 479 | 55521.3 | 1 | UniProt (P09914) Pfam (PF13424) Pfam (PF13181) | Homo sapiens (Human) | IFIT-1,Interferon-induced 56 kDa protein,P56 |
| 2 | B (B) | RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3') | polymer | 4 | 1712.1 | 1 | unidentified | ||
| 3 | C (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 4 | D, E (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A: 1 - 478 (UniProt: P09914)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 216 | Asn 216 | engineered mutation |
| Glu 457 | Leu 457 | engineered mutation |
| Glu 464 | Leu 464 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57233.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 230.3 | |
| All* | Total formula weight | 57463.7 |
