5UDK
 
 | | IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDI
 | | IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap) | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDJ
 | | IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDL
 | | IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap) | | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2016-12-27 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5W5I
 | | Human IFIT1 dimer with PPP-AAAA | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(ATP))-R(P*AP*AP*A)-3') | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2017-06-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
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5W5H
 | | Human IFIT1 dimer with m7Gppp-AAAA | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3') | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2017-06-15 | | Release date: | 2017-07-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
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7UZK
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7UZJ
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6VQJ
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6VQI
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6VQ7
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6VQA
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6VQH
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6VQ9
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6VQ6
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6VQB
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6VQC
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6VQG
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6VQK
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6VQ8
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4HOR
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligocytidine | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(CTP)P*CP*CP*CP*C)-3') | | Authors: | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.861 Å) | | Cite: | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOU
 | | Crystal Structure of N-terminal Human IFIT1 | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 1 | | Authors: | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-30 | | Last modified: | 2013-02-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOT
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligoadenine | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(ATP)P*AP*AP*A)-3') | | Authors: | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOQ
 | | Crystal Structure of Full-Length Human IFIT5 | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 5 | | Authors: | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-23 | | Last modified: | 2013-02-27 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOS
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligouridine | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 5, RNA (5'-R(*(UTP)P*UP*UP*U)-3'), SODIUM ION | | Authors: | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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