5W5I

Human IFIT1 dimer with PPP-AAAA

Summary for 5W5I

• Entry DOI: 10.2210/pdb5w5i/pdb
• Related: 5W5H
• Descriptor: Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(ATP))-R(P*AP*AP*A)-3') (3 entities in total)
• Functional Keywords: triphosphate rna, tetratricopeptide repeat, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : P09914
• Total number of polymer chains: 4
• Total formula weight: 113928.48

Authors

Abbas, Y.M.,Martinez-Montero, S.,Damha, M.J.,Nagar, B. (deposition date: 2017-06-15, release date: 2017-06-28, Last modification date: 2024-03-13)

• Primary citation: Abbas, Y.M.,Martinez-Montero, S.,Cencic, R.,Pelletier, J.,Damha, M.J.,Pawelek, P.D.,Nagar, B.; Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)