3PZP
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![BU of 3pzp by Molmil](/molmil-images/mine/3pzp) | Human DNA polymerase kappa extending opposite a cis-syn thymine dimer | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Vasquez-Del Carpio, R, Silverstein, T.D, Lone, S, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. | Deposit date: | 2010-12-14 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.336 Å) | Cite: | Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer. J.Mol.Biol., 408, 2011
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4EEY
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![BU of 4eey by Molmil](/molmil-images/mine/4eey) | Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ... | Authors: | Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2012-03-28 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy. Nat.Struct.Mol.Biol., 19, 2012
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3Q8P
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![BU of 3q8p by Molmil](/molmil-images/mine/3q8p) | Human DNA polymerase iota incorporating dCTP opposite 8-oxo-guanine | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Kirouac, K.N, Ling, H. | Deposit date: | 2011-01-06 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q8Q
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![BU of 3q8q by Molmil](/molmil-images/mine/3q8q) | Human DNA polymerase iota incorporating dATP opposite 8-oxo-guanine | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Kirouac, K.N, Ling, H. | Deposit date: | 2011-01-06 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.031 Å) | Cite: | Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc.Natl.Acad.Sci.USA, 108, 2011
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6I1L
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![BU of 6i1l by Molmil](/molmil-images/mine/6i1l) | |
3IFZ
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![BU of 3ifz by Molmil](/molmil-images/mine/3ifz) | crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit A, SODIUM ION | Authors: | Piton, J, Aubry, A, Delarue, M, Mayer, C. | Deposit date: | 2009-07-27 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5, 2010
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3Q8R
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![BU of 3q8r by Molmil](/molmil-images/mine/3q8r) | Human DNA polymerase iota incorporating dGTP opposite 8-oxo-guanine | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Kirouac, K.N, Ling, H. | Deposit date: | 2011-01-06 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc.Natl.Acad.Sci.USA, 108, 2011
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3WAZ
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![BU of 3waz by Molmil](/molmil-images/mine/3waz) | Crystal structure of a restriction enzyme PabI in complex with DNA | Descriptor: | ADENINE, DNA (5'-D(*GP*CP*AP*TP*AP*GP*CP*TP*GP*TP*(ORP)P*CP*AP*GP*CP*TP*AP*TP*GP*C)-3'), Putative uncharacterized protein | Authors: | Miyazono, K, Miyakawa, T, Ito, T, Tanokura, M. | Deposit date: | 2013-05-10 | Release date: | 2014-01-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abyssi. Nat Commun, 5, 2014
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8QAM
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![BU of 8qam by Molmil](/molmil-images/mine/8qam) | |
5CDM
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![BU of 5cdm by Molmil](/molmil-images/mine/5cdm) | 2.5A structure of QPT-1 with S.aureus DNA gyrase and DNA | Descriptor: | (2R,4S,4aS)-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1'H,3'H)-trione, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ... | Authors: | Bax, B.D, Srikannathasan, V, Chan, P.F. | Deposit date: | 2015-07-04 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6, 2015
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3OSP
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![BU of 3osp by Molmil](/molmil-images/mine/3osp) | Structure of rev1 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | Authors: | Nair, D.T, Aggarwal, A.K. | Deposit date: | 2010-09-09 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J.Mol.Biol., 406, 2011
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1MWI
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![BU of 1mwi by Molmil](/molmil-images/mine/1mwi) | Crystal structure of a MUG-DNA product complex | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | Authors: | Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H. | Deposit date: | 2002-09-30 | Release date: | 2002-10-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions. Cell(Cambridge,Mass.), 92, 1998
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7LMK
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![BU of 7lmk by Molmil](/molmil-images/mine/7lmk) | |
4B21
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![BU of 4b21 by Molmil](/molmil-images/mine/4b21) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | Descriptor: | 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PHOSPHATE ION, ... | Authors: | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | Deposit date: | 2012-07-12 | Release date: | 2013-01-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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8BP2
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![BU of 8bp2 by Molmil](/molmil-images/mine/8bp2) | 2.8A STRUCTURE OF ZOLIFLODACIN WITH S.AUREUS DNA GYRASE AND DNA | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (20-MER), DNA gyrase subunit A, ... | Authors: | Bax, B.D, Morgan, H, Warren, A.J. | Deposit date: | 2022-11-15 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A 2.8 angstrom Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase. Int J Mol Sci, 24, 2023
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6TYW
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![BU of 6tyw by Molmil](/molmil-images/mine/6tyw) | |
6TYZ
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![BU of 6tyz by Molmil](/molmil-images/mine/6tyz) | |
6TYV
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![BU of 6tyv by Molmil](/molmil-images/mine/6tyv) | |
6TYX
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![BU of 6tyx by Molmil](/molmil-images/mine/6tyx) | |
7W5P
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![BU of 7w5p by Molmil](/molmil-images/mine/7w5p) | Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA | Descriptor: | CcTet, DNA, DNA (12-MER), ... | Authors: | Mu, Y.J, Zhang, L, Zhang, L. | Deposit date: | 2021-11-30 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18, 2022
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7YHS
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![BU of 7yhs by Molmil](/molmil-images/mine/7yhs) | Structure of Csy-AcrIF4-dsDNA | Descriptor: | AcrIF4, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | Authors: | Feng, Y, Zhang, L.X. | Deposit date: | 2022-07-14 | Release date: | 2023-03-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage. J.Biol.Chem., 298, 2022
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6TYU
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![BU of 6tyu by Molmil](/molmil-images/mine/6tyu) | |
4B24
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![BU of 4b24 by Molmil](/molmil-images/mine/4b24) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | Descriptor: | 5'-D(*CP*GP*AP*TP*AP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*TP*AP*TP*CP*GP)-3', PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE 2 | Authors: | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | Deposit date: | 2012-07-12 | Release date: | 2013-01-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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7VW3
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![BU of 7vw3 by Molmil](/molmil-images/mine/7vw3) | Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ... | Authors: | Du, W.H, Qian, J.Q, Huang, Q. | Deposit date: | 2021-11-09 | Release date: | 2023-03-15 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State. Int J Mol Sci, 24, 2023
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6TYT
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![BU of 6tyt by Molmil](/molmil-images/mine/6tyt) | |