7W5P
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA
Summary for 7W5P
Entry DOI | 10.2210/pdb7w5p/pdb |
Descriptor | CcTet, DNA (12-MER), DNA, ... (6 entities in total) |
Functional Keywords | dioxygenase, 5-methylcytosin oxidation, n6-methyldeoxyadenine demethylation, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Coprinopsis cinerea More |
Total number of polymer chains | 8 |
Total formula weight | 208009.67 |
Authors | |
Primary citation | Mu, Y.,Zhang, L.,Hu, J.,Zhou, J.,Lin, H.W.,He, C.,Chen, H.Z.,Zhang, L. A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18:733-741, 2022 Cited by PubMed: 35654845DOI: 10.1038/s41589-022-01041-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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