7VW3

Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex

Summary for 7VW3

Entry DOI	10.2210/pdb7vw3/pdb
EMDB information	32104
Descriptor	CRISPR-associated endonuclease Cas9, single-guide RNA, Target DNA strand, ... (5 entities in total)
Functional Keywords	crispr-cas9, genome editing, dna cleavage, dna binding protein, dna binding protein-rna-dna complex, dna binding protein/rna/dna
Biological source	Staphylococcus aureus More
Total number of polymer chains	4
Total formula weight	178185.49
Authors	Du, W.H.,Qian, J.Q.,Huang, Q. (deposition date: 2021-11-09, release date: 2023-03-15, Last modification date: 2024-06-26)
Primary citation	Du, W.,Zhu, H.,Qian, J.,Xue, D.,Zheng, S.,Huang, Q. Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 36674715 DOI: 10.3390/ijms24021204 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation