3IFZ
crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution
Summary for 3IFZ
Entry DOI | 10.2210/pdb3ifz/pdb |
Related | 1AB4 |
Descriptor | DNA gyrase subunit A, (4S)-2-METHYL-2,4-PENTANEDIOL, SODIUM ION, ... (4 entities in total) |
Functional Keywords | dna gyrase, gyra, breakage and reunion domain, type ii topoisomerase, tuberculosis, quinolone binding site, dna binding site, antibiotic resistance, atp-binding, dna-binding, isomerase, nucleotide-binding, topoisomerase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 114233.07 |
Authors | Piton, J.,Aubry, A.,Delarue, M.,Mayer, C. (deposition date: 2009-07-27, release date: 2010-07-28, Last modification date: 2023-11-01) |
Primary citation | Piton, J.,Petrella, S.,Delarue, M.,Andre-Leroux, G.,Jarlier, V.,Aubry, A.,Mayer, C. Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5:e12245-e12245, 2010 Cited by PubMed: 20805881DOI: 10.1371/journal.pone.0012245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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