3IFZ

crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution

Summary for 3IFZ

Entry DOI	10.2210/pdb3ifz/pdb
Related	1AB4
Descriptor	DNA gyrase subunit A, (4S)-2-METHYL-2,4-PENTANEDIOL, SODIUM ION, ... (4 entities in total)
Functional Keywords	dna gyrase, gyra, breakage and reunion domain, type ii topoisomerase, tuberculosis, quinolone binding site, dna binding site, antibiotic resistance, atp-binding, dna-binding, isomerase, nucleotide-binding, topoisomerase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	114233.07
Authors	Piton, J.,Aubry, A.,Delarue, M.,Mayer, C. (deposition date: 2009-07-27, release date: 2010-07-28, Last modification date: 2023-11-01)
Primary citation	Piton, J.,Petrella, S.,Delarue, M.,Andre-Leroux, G.,Jarlier, V.,Aubry, A.,Mayer, C. Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5:e12245-e12245, 2010 Cited by PubMed: 20805881 DOI: 10.1371/journal.pone.0012245 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation