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3IFZ

crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003918molecular_functionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A0005524molecular_functionATP binding
A0006259biological_processDNA metabolic process
A0006265biological_processDNA topological change
B0003677molecular_functionDNA binding
B0003918molecular_functionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B0005524molecular_functionATP binding
B0006259biological_processDNA metabolic process
B0006265biological_processDNA topological change
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MPD A 509
ChainResidue
ALEU105
AASN176
ASER178

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE NA A 510
ChainResidue
ALYS396
AGLN431

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MPD B 509
ChainResidue
BSER178
BHOH589
BARG98
BLEU105
BLEU109
BGLY177

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE NA B 510
ChainResidue
BLYS396
BGLN431

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|HAMAP-Rule:MF_01897
ChainResidueDetails
ATYR129
BTYR129

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609
ChainResidueDetails
ATHR2
BTHR2

226707

PDB entries from 2024-10-30

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