8SLF
 
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8SLE
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-3 | | Descriptor: | Transient receptor potential cation channel subfamily M member 5 | | Authors: | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | Deposit date: | 2023-04-21 | | Release date: | 2024-07-03 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SLD
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8SLC
 | | High Affinity nanobodies against GFP | | Descriptor: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | | Authors: | Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C. | | Deposit date: | 2023-04-21 | | Release date: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | High Affinity nanobodies against GFP
To Be Published
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8SLB
 | | X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12 | | Descriptor: | CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ... | | Authors: | Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A. | | Deposit date: | 2023-04-21 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
J.Mol.Biol., 435, 2023
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8SLA
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-2 | | Descriptor: | Transient receptor potential cation channel subfamily M member 5 | | Authors: | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | Deposit date: | 2023-04-21 | | Release date: | 2024-07-03 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL9
 | | Crystal structure of Francisella tularensis HPPK-DHPS in complex with HPPK inhibitor HP-73 | | Descriptor: | 1,2-ETHANEDIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine, ... | | Authors: | Shaw, G.X, Shi, G, Cherry, S, Needle, D, Tropea, J.E, Waugh, D.S, Ji, X. | | Deposit date: | 2023-04-21 | | Release date: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of Francisella tularensis HPPK-DHPS in complex with HPPK inhibitor HP-73
To be published
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8SL8
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-1 | | Descriptor: | Transient receptor potential cation channel subfamily M member 5 | | Authors: | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | Deposit date: | 2023-04-21 | | Release date: | 2024-07-03 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL7
 | | Butyricicoccus sp. BIOML-A1 tryptophanase complex with (3S) ALG-05 | | Descriptor: | (E)-3-[(3S)-3-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, Tryptophanase | | Authors: | Graboski, A.L, Redinbo, M.R. | | Deposit date: | 2023-04-21 | | Release date: | 2023-08-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
Cell Chem Biol, 30, 2023
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8SL6
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8SL5
 | | [2T13] Self-assembling left-handed two-turn tensegrity triangle with 13 interjunction base pairs and R3 symmetry | | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*A)-3'), ... | | Authors: | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | | Deposit date: | 2023-04-21 | | Release date: | 2024-04-24 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (6.55 Å) | | Cite: | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL4
 | | Dimeric form of human adenylyl cyclase 5 | | Descriptor: | Adenylate cyclase type 5 | | Authors: | Yen, Y.C, Tesmer, J.J.G. | | Deposit date: | 2023-04-20 | | Release date: | 2024-04-03 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Structure of adenylyl cyclase 5 in complex with G beta gamma offers insights into ADCY5-related dyskinesia.
Nat.Struct.Mol.Biol., 2024
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8SL3
 | | Human adenylyl Cyclase 5 in complex with Gbg | | Descriptor: | Adenylate cyclase type 5, GERAN-8-YL GERAN, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Yen, Y.C, Tesmer, J.J.G. | | Deposit date: | 2023-04-20 | | Release date: | 2024-04-03 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Structure of adenylyl cyclase 5 in complex with G beta gamma offers insights into ADCY5-related dyskinesia.
Nat.Struct.Mol.Biol., 2024
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8SL1
 | | Cryo-EM structure of PAPP-A2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Judge, R.A, Stoll, V.S, Eaton, D, Hao, Q, Bratkowski, M.A. | | Deposit date: | 2023-04-20 | | Release date: | 2023-11-08 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition.
Commun Chem, 6, 2023
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8SL0
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8SKY
 | | Crystal structure of YisK from Bacillus subtilis in complex with oxalate | | Descriptor: | Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION, OXALATE ION | | Authors: | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | | Deposit date: | 2023-04-20 | | Release date: | 2023-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization.
J.Bacteriol., 206, 2024
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8SKX
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8SKW
 | | MicroED structure of d(CGCGCG)2 Z-DNA | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE | | Authors: | Haymaker, A, Bardin, A.A, Martynowycz, M.W, Nannenga, B.L. | | Deposit date: | 2023-04-20 | | Release date: | 2023-08-16 | | Last modified: | 2023-12-20 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | | Cite: | Structure determination of a DNA crystal by MicroED.
Structure, 31, 2023
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8SKV
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8SKU
 | | Structure of human SIgA1 in complex with human CD89 (FcaR1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | Authors: | Liu, Q, Stadtmueller, B.M. | | Deposit date: | 2023-04-20 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
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8SKT
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8SKS
 | | human liver mitochondrial Superoxide dismutase [Mn] | | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | Authors: | Zhang, Z, Tringides, M. | | Deposit date: | 2023-04-20 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Mol.Cell Proteomics, 22, 2023
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8SKR
 | | human liver mitochondrial Aspartate aminotransferase | | Descriptor: | Aspartate aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Zhang, Z, Tringides, M. | | Deposit date: | 2023-04-20 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Mol.Cell Proteomics, 22, 2023
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8SKQ
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8SKP
 | | X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia in complex with 1-hydroxypyridine-2(1H)-thione-6-carboxylic acid | | Descriptor: | 1,2-ETHANEDIOL, 1-hydroxy-6-sulfanylidene-1,6-dihydropyridine-2-carboxylic acid, Metallo-beta-lactamase type 2, ... | | Authors: | Thoden, J.B, Holden, H.M. | | Deposit date: | 2023-04-20 | | Release date: | 2023-08-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.
J.Biol.Chem., 299, 2023
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