8SL8

Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-1

Summary for 8SL8

Entry DOI	10.2210/pdb8sl8/pdb
EMDB information	40575 40600
Descriptor	Transient receptor potential cation channel subfamily M member 5 (1 entity in total)
Functional Keywords	ion channel, transient receptor potential, trp, transient receptor potential melastatin 5, trpm5, membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	529406.88
Authors	Karuppan, S.,Schrag, L.G.,Jara-Oseguera, A.,Zubcevic, L. (deposition date: 2023-04-21, release date: 2024-07-03, Last modification date: 2024-07-10)
Primary citation	Karuppan, S.,Schrag, L.G.,Pastrano, C.M.,Jara-Oseguera, A.,Zubcevic, L. Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. Proc.Natl.Acad.Sci.USA, 121:e2403333121-e2403333121, 2024 Cited by PubMed: 38923985 DOI: 10.1073/pnas.2403333121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation