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7CJB
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BU of 7cjb by Molmil
VHL recognizes hydroxyproline in RIPK1
Descriptor: Elongin-B, Elongin-C, GLYCEROL, ...
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:VHL recognizes hydroxyproline in RIPK1
To Be Published
7DNJ
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BU of 7dnj by Molmil
K63-polyUb MDA5CARDs complex
Descriptor: Interferon-induced helicase C domain-containing protein 1, Ubiquitin
Authors:Song, B, Chen, Y, Luo, D.H, Zheng, J.
Deposit date:2020-12-09
Release date:2021-10-13
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
7DNI
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BU of 7dni by Molmil
MDA5 CARDs-MAVS CARD polyUb complex
Descriptor: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin
Authors:Song, B, Chen, Y, Luo, D.H, Zheng, J.
Deposit date:2020-12-09
Release date:2021-10-13
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
4FBJ
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BU of 4fbj by Molmil
Structure of the Cif:Nedd8 complex - Photorhabdus luminescens Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: CHLORIDE ION, Hypothetical protein, NEDD8
Authors:Crow, A, Banfield, M.J.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
4FN2
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BU of 4fn2 by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ37
Descriptor: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-06-19
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4G50
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BU of 4g50 by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ168
Descriptor: 1,2-ETHANEDIOL, 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, FORMIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-07-17
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4FJV
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BU of 4fjv by Molmil
Crystal Structure of Human Otubain2 and Ubiquitin Complex
Descriptor: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ...
Authors:Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M.
Deposit date:2012-06-12
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
4GGQ
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BU of 4ggq by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with CJ40
Descriptor: 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-07
Release date:2012-08-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4GIV
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BU of 4giv by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ183
Descriptor: 3-(pyridin-3-yl)propyl (2S)-1-[(3-nitrophenyl)sulfonyl]piperidine-2-carboxylate, FORMIC ACID, Ubiquitin-like protein SMT3, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-09
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4F8C
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BU of 4f8c by Molmil
Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8
Authors:Crow, A, Banfield, M.
Deposit date:2012-05-17
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
4HCN
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BU of 4hcn by Molmil
Crystal structure of Burkholderia pseudomallei effector protein CHBP in complex with ubiquitin
Descriptor: DI(HYDROXYETHYL)ETHER, FORMIC ACID, PHOSPHATE ION, ...
Authors:Yao, Q, Cui, J, Zhu, Y, Shao, F.
Deposit date:2012-09-30
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HCP
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BU of 4hcp by Molmil
crystal structure of Burkholderia pseudomallei effector protein chbp in complex with nedd8
Descriptor: GLYCEROL, NEDD8, Putative ATP/GTP binding protein, ...
Authors:Yao, Q, Shao, F.
Deposit date:2012-10-01
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
1R4M
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BU of 1r4m by Molmil
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex
Descriptor: Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ...
Authors:Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
Deposit date:2003-10-07
Release date:2003-12-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1UEL
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BU of 1uel by Molmil
Solution structure of ubiquitin-like domain of hHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5a
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog B
Authors:Fujiwara, K, Tenno, T, Jee, J.G, Sugasawa, K, Ohki, I, Kojima, C, Tochio, H, Hiroaki, H, Hanaoka, H, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-19
Release date:2004-02-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B
J.Biol.Chem., 279, 2004
1R4N
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BU of 1r4n by Molmil
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Ubiquitin-like protein NEDD8, ZINC ION, ...
Authors:Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
Deposit date:2003-10-07
Release date:2003-12-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1S1Q
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BU of 1s1q by Molmil
TSG101(UEV) domain in complex with Ubiquitin
Descriptor: ACETIC ACID, COPPER (II) ION, SULFATE ION, ...
Authors:Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P.
Deposit date:2004-01-07
Release date:2004-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ubiquitin recognition by the human TSG101 protein
Mol.Cell, 13, 2004
1UZX
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BU of 1uzx by Molmil
A complex of the Vps23 UEV with ubiquitin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, UBIQUITIN, ...
Authors:Teo, H, Williams, R.L.
Deposit date:2004-03-18
Release date:2004-03-30
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights Into Endosomal Sorting Complex Required for Transport (Escrt-I) Recognition of Ubiquitinated Proteins
J.Biol.Chem., 279, 2004
1VCB
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BU of 1vcb by Molmil
THE VHL-ELONGINC-ELONGINB STRUCTURE
Descriptor: PROTEIN (ELONGIN B), PROTEIN (ELONGIN C), PROTEIN (VHL)
Authors:Stebbins, C.E, Kaelin, W.G, Pavletich, N.P.
Deposit date:1999-03-13
Release date:1999-04-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function.
Science, 284, 1999
4ZFR
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BU of 4zfr by Molmil
Catalytic domain of Sst2 F403A mutant bound to ubiquitin
Descriptor: 1,2-ETHANEDIOL, AMSH-like protease sst2, ZINC ION, ...
Authors:Shrestha, R.K.
Deposit date:2015-04-21
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of Catalytic domain of Sst2 F403A mutant bound to ubiquitin at 1.7 Angstroms
To Be Published
4ZFT
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BU of 4zft by Molmil
Catalytic domain of Sst2 F403W mutant bound to ubiquitin
Descriptor: 1,2-ETHANEDIOL, AMSH-like protease sst2, Polyubiquitin-B, ...
Authors:Bueno, A.N.
Deposit date:2015-04-21
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Structure of the catalytic domain of Sst2 mutant F403W bound to ubiquitin at 2.3 Angstroms
To Be Published
5B83
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BU of 5b83 by Molmil
Crystal structure of Optineurin UBAN in complex with linear ubiquitin
Descriptor: Optineurin, tetra ubiquitin
Authors:Ishii, R, Nureki, O.
Deposit date:2016-06-12
Release date:2016-09-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
Nat Commun, 7, 2016
4ZYN
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BU of 4zyn by Molmil
Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130)
Descriptor: E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION
Authors:Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K.
Deposit date:2015-05-21
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:A Ubl/ubiquitin switch in the activation of Parkin.
Embo J., 34, 2015
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
Descriptor: TRABID, UBIQUITIN, ZINC ION
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
2ZVN
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BU of 2zvn by Molmil
NEMO CoZi domain incomplex with diubiquitin in P212121 space group
Descriptor: NF-kappa-B essential modulator, UBC protein
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
2ZVO
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BU of 2zvo by Molmil
NEMO CoZi domain in complex with diubiquitin in C2 space group
Descriptor: NF-kappa-B essential modulator, UBC protein
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009

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數據於2024-09-18公開中

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