6XZ1
Conjugate of the HECT domain of HUWE1 with ubiquitin
Summary for 6XZ1
Entry DOI | 10.2210/pdb6xz1/pdb |
Descriptor | HECT, UBA and WWE domain containing 1, isoform CRA_a, Polyubiquitin-B, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | ubiquitin ligase, e3 enzyme, ubiquitin-propargylamide, activity-based probe, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 107826.82 |
Authors | Liu, B.,Seenivasan, A.,Nair, R.,Chen, D.,Lowe, E.D.,Lorenz, S. (deposition date: 2020-01-31, release date: 2021-08-25, Last modification date: 2024-01-24) |
Primary citation | Nair, R.M.,Seenivasan, A.,Liu, B.,Chen, D.,Lowe, E.D.,Lorenz, S. Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe. Acs Chem.Biol., 16:1615-1621, 2021 Cited by PubMed: 34403242DOI: 10.1021/acschembio.1c00433 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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