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6XZ1

Conjugate of the HECT domain of HUWE1 with ubiquitin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
HECT, UBA and WWE domain containing 1, isoform CRA_apolymer38445099.12UniProt (A0A024R9Y3)
Pfam (PF00632)
UniProt (by SIFTS) (Q5H924)
Homo sapiens (Human)
2B, D
(C, D)
Polyubiquitin-Bpolymer758519.82UniProt (P0CG47)
Pfam (PF00240)
Homo sapiens (Human)
3E, F, H, I, K
(A, B, D)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
4G, J
(C, D)
prop-2-en-1-aminenon-polymer57.12Chemie (AYE)
5L, M, N, O
(A, C, B, D)
waterwater18.0162Chemie (HOH)
Sequence modifications
A, B: 3993 - 4374 (UniProt: A0A024R9Y3)
PDBExternal DatabaseDetails
Gly 3991-expression tag
Pro 3992-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight107237.8
Non-Polymers*Number of molecules7
Total formula weight589.0
All*Total formula weight107826.8
*Water molecules are not included.

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PDB entries from 2025-12-03

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