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5JMQ	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP3 Descriptor: 1,2-ETHANEDIOL, 9-[(5E)-7-carbamimidamido-5,6,7-trideoxy-beta-D-ribo-hept-5-enofuranosyl]-9H-purin-6-amine, CALCIUM ION, ... Authors: Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. Deposit date: 2016-04-29 Release date: 2017-05-10 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.795 Å) Cite: Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. Febs J., 284, 2017
3EHR	Crystal Structure of Human Osteoclast Stimulating Factor Descriptor: Osteoclast-stimulating factor 1 Authors: Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. Deposit date: 2008-09-14 Release date: 2009-08-04 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
4ORZ	HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain Descriptor: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19 Authors: Geyer, M, Lulf, S. Deposit date: 2014-02-12 Release date: 2014-03-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody. Retrovirology, 11, 2014
4N78	The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton Descriptor: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ... Authors: Chen, Z.C. Deposit date: 2013-10-15 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.43 Å) Cite: The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton. Cell(Cambridge,Mass.), 156, 2014
3NMZ	Crystal structure of APC complexed with Asef Descriptor: APC variant protein, Rho guanine nucleotide exchange factor 4 Authors: Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. Deposit date: 2010-06-23 Release date: 2011-07-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
5NUH	Crystal structure of SIVmac239 Nef bound to an engineered Hck SH3 domain Descriptor: Protein Nef, Tyrosine-protein kinase HCK,Tyrosine-protein kinase HCK Authors: Horenkamp, F.A, Anand, K, Geyer, M. Deposit date: 2017-04-30 Release date: 2017-08-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3. Nat Commun, 8, 2017
3EHQ	Crystal Structure of Human Osteoclast Stimulating Factor Descriptor: 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 Authors: Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. Deposit date: 2008-09-14 Release date: 2009-08-04 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
5FWD	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP2 Descriptor: 1,2-ETHANEDIOL, 9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine, CALCIUM ION, ... Authors: Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. Deposit date: 2016-02-12 Release date: 2017-03-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Studies of Protein Arginine Methyltransferase 2 Reveal its Interactions with Potential Substrates and Inhibitors. FEBS J., 284, 2017
5FWA	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP1 Descriptor: 1,2-ETHANEDIOL, 9-(6-carbamimidamido-5,6-dideoxy-beta-D-ribo-hexofuranosyl)-9H-purin-6-amine, CALCIUM ION, ... Authors: Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. Deposit date: 2016-02-16 Release date: 2016-11-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. FEBS J., 284, 2017
5FUL	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with SAH Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... Authors: Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. Deposit date: 2016-01-27 Release date: 2016-11-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. FEBS J., 284, 2017
3TVT	Structural basis for Discs Large interaction with Pins Descriptor: Disks large 1 tumor suppressor protein, Partner of Inscuteable Authors: Johnston, C.A, Doe, C.Q, Prehoda, K.E. Deposit date: 2011-09-20 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for Discs Large interaction with Pins To be Published
3UAT	Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules Descriptor: Disks large homolog 1, phosphor-LGN peptide Authors: Shang, Y, Zhu, J, Wen, W, Zhang, M. Deposit date: 2011-10-22 Release date: 2011-12-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules Embo J., 2011
1AVZ	V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN Descriptor: FYN TYROSINE KINASE, NEGATIVE FACTOR Authors: Arold, S, Franken, P, Dumas, C. Deposit date: 1997-09-23 Release date: 1998-03-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3 Å) Cite: The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. Structure, 5, 1997
2ROL	Structural Basis of PxxDY motif recognition in SH3 binding Descriptor: 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1 Authors: Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P. Deposit date: 2008-04-02 Release date: 2009-03-03 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis of PxxDY motif recognition in SH3 binding J.Mol.Biol., 382, 2008
2XKX	Single particle analysis of PSD-95 in negative stain Descriptor: DISKS LARGE HOMOLOG 4 Authors: Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M. Deposit date: 2010-07-15 Release date: 2011-07-20 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING Cite: Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95 Biochim.Biophys.Acta, 1808, 2011
1NG2	Structure of autoinhibited p47phox Descriptor: Neutrophil cytosolic factor 1 Authors: Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. Deposit date: 2002-12-16 Release date: 2003-05-20 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular basis of phosphorylation-induced activation of the NADPH oxidase Cell(Cambridge,Mass.), 113, 2003
1K4U	Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox Descriptor: PHAGOCYTE NADPH OXIDASE SUBUNIT P47PHOX, PHAGOCYTE NADPH OXIDASE SUBUNIT P67PHOX Authors: Kami, K, Takeya, R, Sumimoto, H, Kohda, D. Deposit date: 2001-10-08 Release date: 2002-04-08 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p. EMBO J., 21, 2002
1JXM	CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANIDINE, GUANOSINE-5'-MONOPHOSPHATE, ... Authors: Tavares, G.A, Panepucci, E.H, Brunger, A.T. Deposit date: 2001-09-07 Release date: 2002-01-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95. Mol.Cell, 8, 2001
1KJW	SH3-Guanylate Kinase Module from PSD-95 Descriptor: POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION Authors: McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E. Deposit date: 2001-12-05 Release date: 2002-01-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins Mol.Cell, 8, 2001
1JXO	Crystal Structure of the SH3-HOOK-GK Fragment of PSD-95 Descriptor: postsynaptic density protein Authors: Tavares, G.A, Panepucci, E.H, Brunger, A.T. Deposit date: 2001-09-07 Release date: 2002-01-16 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95. Mol.Cell, 8, 2001
1EFN	HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN Descriptor: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION Authors: Lee, C.-H, Kuriyan, J. Deposit date: 1996-06-29 Release date: 1997-01-11 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell(Cambridge,Mass.), 85, 1996
2MOX	solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1 Descriptor: Sorbin and SH3 domain-containing protein 1 Authors: Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q. Deposit date: 2014-05-07 Release date: 2014-05-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
2LZ6	Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications Descriptor: CD2-associated protein, Ubiquitin Authors: Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N. Deposit date: 2012-09-24 Release date: 2013-10-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. Plos One, 8, 2013
2PZ1	Crystal Structure of Auto-inhibited Asef Descriptor: Rho guanine nucleotide exchange factor 4 Authors: Betts, L, Sondek, J, Rossman, K.L. Deposit date: 2007-05-17 Release date: 2007-08-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. Nat.Struct.Mol.Biol., 14, 2007
2L3S	Structure of the autoinhibited Crk Descriptor: Autoinhibited Crk protein Authors: Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R. Deposit date: 2010-09-21 Release date: 2010-12-08 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis for regulation of the Crk signaling protein by a proline switch. Nat.Chem.Biol., 7, 2011

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