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2IEG
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Crystal structure of rabbit muscle glycogen phosphorylase in complex with 3,4-dihydro-2-quinolone
Descriptor: (2S)-N-[(3S)-1-(2-AMINO-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-2-CHLORO-2H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Glycogen phosphorylase, ...
Authors:Birch, A.M, Kenny, P.W, Oikonomakos, N.G, Otterbein, L, Schofield, P, Whittamore, P.R.O, Whalley, D.P, Rowsell, S, Pauptit, R, Pannifer, A, Breed, J, Minshull, C.
Deposit date:2006-09-19
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2IEH
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Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF11, ...
Authors:Garcia-Saez, I, Kozielski, F.
Deposit date:2006-09-19
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration.
J.Biol.Chem., 282, 2007
2IEI
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Crystal structure of rabbit muscle glycogen phosphorylase in complex with 3,4-dihydro-2-quinolone
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, (S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE, Glycogen phosphorylase, ...
Authors:Birch, A.M, Kenny, P.W, Oikonomakos, N.G, Otterbein, L, Schofield, P, Whittamore, P.R.O, Whalley, D.P, Rowsell, S, Pauptit, R, Pannifer, A, Breed, J, Minshull, C.
Deposit date:2006-09-19
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2IEJ
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Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A Resolution
Descriptor: ACETATE ION, METHYL N-{(3S)-1-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-6-PHENYL-1,2,3,4-TETRAHYDROQUINOLIN-3-YL}-N-[(1-METHYL-1H-IMIDAZOL-4-YL)SULFONYL]GLYCINATE, Protein farnesyltransferase subunit beta, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2006-09-19
Release date:2007-01-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase.
Mol.Biochem.Parasitol., 152, 2007
2IEK
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BU of 2iek by Molmil
New crystal form of transcriptional regulator tm1030 from Thermotoga maritima
Descriptor: HEXAETHYLENE GLYCOL, Transcriptional regulator, TetR family
Authors:Koclega, K.D, Chruszcz, M, Minor, W.
Deposit date:2006-09-19
Release date:2007-08-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:New crystal form of transcriptional regulator tm1030 from Thermotoga maritima
To be Published
2IEL
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CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus
Descriptor: Hypothetical Protein TT0030
Authors:Zhu, J, Huang, J, Stepanyuk, G, Chen, L, Chang, J, Zhao, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-09-19
Release date:2006-11-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
2IEM
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BU of 2iem by Molmil
Solution structure of an oxidized form (Cys51-Cys198) of E. coli Methionine Sulfoxide Reductase A (MsrA)
Descriptor: Peptide methionine sulfoxide reductase msrA
Authors:Coudevylle, N, Antoine, M, Bouguet-Bonnet, S, Mutzenhardt, P, Boschi-Muller, S, Branlant, G, Cung, M.T.
Deposit date:2006-09-19
Release date:2007-02-13
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the Reduced Form and an Oxidized Form of E. coli Methionine Sulfoxide Reductase A (MsrA): Structural Insight of the MsrA Catalytic Cycle.
J.Mol.Biol., 366, 2007
2IEN
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Crystal structure analysis of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017)
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ...
Authors:Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T.
Deposit date:2006-09-19
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains.
J.Mol.Biol., 338, 2004
2IEO
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Crystal structure analysis of HIV-1 protease mutant I84V with a potent non-peptide inhibitor (UIC-94017)
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Protease, ...
Authors:Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T.
Deposit date:2006-09-19
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains.
J.Mol.Biol., 338, 2004
2IEP
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BU of 2iep by Molmil
Crystal structure of immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
Descriptor: Muscle-specific kinase receptor, SULFATE ION
Authors:Stiegler, A.L, Burden, S.J, Hubbard, S.R.
Deposit date:2006-09-19
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK
J.Mol.Biol., 364, 2006
2IEQ
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BU of 2ieq by Molmil
Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
Descriptor: ACETATE ION, SODIUM ION, Spike glycoprotein
Authors:Liu, J.
Deposit date:2006-09-19
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
Biochemistry, 45, 2006
2IER
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BU of 2ier by Molmil
Crystal Structure of Aquifex aeolicus LpxC Complexed with Uridine 5'-Diphosphate
Descriptor: GLYCEROL, PALMITIC ACID, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ...
Authors:Gennadios, H.A, Christianson, D.W.
Deposit date:2006-09-19
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
Biochemistry, 45, 2006
2IES
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BU of 2ies by Molmil
Crystal Structure of Aquifex aeolicus LpxC Complexed with Pyrophosphate
Descriptor: CHLORIDE ION, PALMITIC ACID, PYROPHOSPHATE 2-, ...
Authors:Gennadios, H.A, Christianson, D.W.
Deposit date:2006-09-19
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
Biochemistry, 45, 2006
2IEW
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BU of 2iew by Molmil
Crystal structure of Inositol Phosphate Multikinase Ipk2 from S. cerevisiae
Descriptor: CALCIUM ION, Inositol polyphosphate multikinase
Authors:Holmes, W, Jogl, G.
Deposit date:2006-09-19
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity.
J.Biol.Chem., 281, 2006
2IEX
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BU of 2iex by Molmil
Crystal structure of dihydroxynapthoic acid synthetase (GK2873) from Geobacillus kaustophilus HTA426
Descriptor: Dihydroxynapthoic acid synthetase
Authors:Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, BaBa, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-19
Release date:2007-10-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of dihydroxynapthoic acid synthetase (GK2873) from Geobacillus kaustophilus HTA426
To be Published
2IEY
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BU of 2iey by Molmil
Crystal Structure of mouse Rab27b bound to GDP in hexagonal space group
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-27B
Authors:Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IEZ
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Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-27B
Authors:Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IF0
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BU of 2if0 by Molmil
Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-27B
Authors:Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IF1
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BU of 2if1 by Molmil
HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Descriptor: EIF1
Authors:Fletcher, C.M, Hellen, C.U.T, Pestova, T.V, Wagner, G.
Deposit date:1998-08-04
Release date:1999-05-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and interactions of the translation initiation factor eIF1.
EMBO J., 18, 1999
2IF2
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BU of 2if2 by Molmil
Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.
Descriptor: 1,2-ETHANEDIOL, Dephospho-CoA kinase, SULFATE ION
Authors:Forouhar, F, Hussain, M, Seetharaman, J, Hussain, A, Wu, M, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Rost, B, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-09-19
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:

2IF4
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Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana
Descriptor: ATFKBP42
Authors:Granzin, J, Eckhoff, A, Weiergraeber, O.H.
Deposit date:2006-09-20
Release date:2006-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of a Multi-domain Immunophilin from Arabidopsis thaliana: A Paradigm for Regulation of Plant ABC Transporters.
J.Mol.Biol., 364, 2006
2IF5
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Structure of the POZ domain of human LRF, a master regulator of oncogenesis
Descriptor: PRASEODYMIUM ION, Zinc finger and BTB domain-containing protein 7A
Authors:Schubot, F.D, Waugh, D.S, Tropea, J.
Deposit date:2006-09-20
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the POZ domain of human LRF, a master regulator of oncogenesis.
Biochem.Biophys.Res.Commun., 351, 2006
2IF6
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Crystal structure of metalloprotein yiiX from Escherichia coli O157:H7, DUF1105
Descriptor: Hypothetical protein yiiX, UNKNOWN ATOM OR ION
Authors:Bonanno, J.B, Gilmore, J, Bain, K.T, Powell, A, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-09-20
Release date:2006-10-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of hypothetical metalloprotein yiiX from Escherichia coli O157:H7
To be Published
2IF7
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Crystal Structure of NTB-A
Descriptor: CALCIUM ION, CHLORIDE ION, SLAM family member 6
Authors:Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C.
Deposit date:2006-09-20
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
2IF8
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BU of 2if8 by Molmil
Crystal structure of Inositol Phosphate Multikinase Ipk2 in complex with ADP and Mn2+ from S. cerevisiae
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Inositol polyphosphate multikinase, ...
Authors:Holmes, W, Jogl, G.
Deposit date:2006-09-20
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity.
J.Biol.Chem., 281, 2006

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數據於2024-10-09公開中

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