PDB: 19040 resultsInfo pagesStatus searchChemie searchBIRD

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5WEC	Structure of an alternative pilotin from the type II secretion system of Vibrio cholerae Descriptor: Lipoprotein Authors: Williamson, Z.A, Reed, R.W, Korotkov, K.V. Deposit date: 2017-07-08 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.563 Å) Cite: Structure and function of a new pilotin from the type II secretion system of Vibrio cholerae To Be Published
5VOS	VGSNKGAIIGL from Amyloid Beta determined by MicroED Descriptor: Amyloid beta A4 protein Authors: Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S, Griner, S.L, Gonen, T. Deposit date: 2017-05-03 Release date: 2018-01-03 Last modified: 2024-03-13 Method: ELECTRON CRYSTALLOGRAPHY (1.42 Å) Cite: Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., 293, 2018
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OOW	The crystal structure of 4-ethylbenzoate bound to T252A mutant of CYP199A4 Descriptor: 4-ethylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... Authors: Coleman, T, Bruning, J.B, Bell, S.G. Deposit date: 2019-04-23 Release date: 2020-04-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural investigation of the interplay between the substrate and the acid-alcohol pair of residues in cytochrome P450 enzymes To Be Published
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OOX	The crystal structure of 4-isopropylbenzoate bound to T252A mutant of CYP199A4 Descriptor: 4-propan-2-ylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... Authors: Coleman, T, Bruning, J.B, Bell, S.G. Deposit date: 2019-04-23 Release date: 2020-04-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.774 Å) Cite: Structural investigation of the interplay between the substrate and the acid-alcohol pair of residues in cytochrome P450 enzymes To Be Published
6NLY	Fragment of human mitochondrial Alanyl-tRNA Synthetase C-Ala domain Descriptor: Alanine--tRNA ligase, mitochondrial Authors: Kuhle, B, Schimmel, P. Deposit date: 2019-01-09 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.307 Å) Cite: Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs. Nat Commun, 11, 2020
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-18 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5VYC	Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A. Deposit date: 2017-05-24 Release date: 2017-07-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (6 Å) Cite: Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep, 20, 2017
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5UTM	Mutant Structures of Streptococcus Agalactiae GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Schormann, N, Ulett, G.C, Chattopadhyay, D. Deposit date: 2017-02-15 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Mutant Structures of Streptococcus agalactiae GAPDH To Be Published
5XPT	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal Descriptor: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B Authors: Hara, K, Taharazako, S, Hashimoto, H. Deposit date: 2017-06-05 Release date: 2017-09-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.102 Å) Cite: Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal Descriptor: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B Authors: Hara, K, Taharazako, S, Hashimoto, H. Deposit date: 2017-06-05 Release date: 2017-09-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.304 Å) Cite: Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
8GUZ	Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations Descriptor: 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain Authors: Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. Deposit date: 2022-09-14 Release date: 2023-06-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
8GV2	Crystal structure of anti-FX IgG fab without FAST-Ig mutations Descriptor: 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain Authors: Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. Deposit date: 2022-09-14 Release date: 2023-06-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.274 Å) Cite: Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
8GTL	Crystal Structure of Cytochrome P450 (CYP101D5) Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 CYP101D5 Authors: Do, H, Lee, J.H. Deposit date: 2022-09-08 Release date: 2022-12-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal Structure and Biochemical Analysis of a Cytochrome P450 CYP101D5 from Sphingomonas echinoides. Int J Mol Sci, 23, 2022
8G89	HSD17B13 in complex with cofactor and inhibitor Descriptor: 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Liu, S. Deposit date: 2023-02-17 Release date: 2023-08-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.222 Å) Cite: Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
8G84	Crystal structures of HSD17B13 complexes Descriptor: Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Liu, S. Deposit date: 2023-02-17 Release date: 2023-08-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.467 Å) Cite: Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
8HG9	Cytochrome P450 steroid hydroxylase (BaCYP106A6) from Bacillus species Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 steroid hydroxylase Authors: Do, H, Lee, J.H. Deposit date: 2022-11-14 Release date: 2023-07-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase ( Ba CYP106A6) from Bacillus Species. J Microbiol Biotechnol., 33, 2023
8HEA	Esterase2 (EaEst2) from Exiguobacterium antarcticum Descriptor: Thermostable carboxylesterase Est30 Authors: Hwang, J, Lee, J.H. Deposit date: 2022-11-08 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structural and Biochemical Insights into Bis(2-hydroxyethyl) Terephthalate Degrading Carboxylesterase Isolated from Psychrotrophic Bacterium Exiguobacterium antarcticum. Int J Mol Sci, 24, 2023
8H38	Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.25 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
5CXT	Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Unknown at 2.20 A resolution Descriptor: RNA-binding protein 39, Splicing factor U2AF 65 kDa subunit Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2015-07-29 Release date: 2015-10-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex. Acta Crystallogr D Struct Biol, 72, 2016

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