PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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2JEA	Structure of a 9-subunit archaeal exosome bound to RNA Descriptor: EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2, EXOSOME COMPLEX RNA-BINDING PROTEIN 1, ... Authors: Lorentzen, E, Conti, E. Deposit date: 2007-01-16 Release date: 2007-04-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.33 Å) Cite: RNA Channelling by the Archaeal Exosome. Embo Rep., 8, 2007
8CSZ	IscB and wRNA bound to Target DNA Descriptor: DNA non-target strand, DNA target strand, IscB, ... Authors: Schuler, G.A, Hu, C, Ke, A. Deposit date: 2022-05-13 Release date: 2022-06-15 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376, 2022
8CTL	IscB and wRNA bound to Target DNA (locked state) Descriptor: DNA non-target strand, DNA target strand, IscB, ... Authors: Schuler, G.A, Hu, C, Ke, A. Deposit date: 2022-05-16 Release date: 2022-06-15 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376, 2022
6WN2	Tyrosyl t-RNA Synthetase Mutant from E.coli Complexed with sulfotyrosine Descriptor: O-SULFO-L-TYROSINE, SODIUM ION, SULFATE ION, ... Authors: Beltran, D.G, Zhang, L. Deposit date: 2020-04-22 Release date: 2020-09-02 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Functional genetic encoding of sulfotyrosine in mammalian cells. Nat Commun, 11, 2020
8KAG	Crystal structure of SpyCas9 in complex with sgRNA and target RNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER) Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.88 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025
7PDU	Pre-catalytic complex of 10-23 DNAzyme with RNA target Descriptor: 10-23 DNAzyme (33-MER), RNA target (19-MER) Authors: Etzkorn, M, Borggrafe, J, Viegas, A. Deposit date: 2021-08-07 Release date: 2021-12-15 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Time-resolved structural analysis of an RNA-cleaving DNA catalyst. Nature, 601, 2022
6OZP	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+ Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ... Authors: Samara, N.L, Yang, W. Deposit date: 2019-05-15 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZS	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 90 min soak in 10 mM Mg2+ Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ... Authors: Samara, N.L, Yang, W. Deposit date: 2019-05-15 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
7NTO	The structure of RRM domain of human TRMT2A at 1.23 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... Authors: Witzenberger, M, Janowski, R, Davydova, E, Niessing, D. Deposit date: 2021-03-10 Release date: 2022-01-19 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death. Comput Struct Biotechnol J, 20, 2022
7NTN	The structure of RRM domain of human TRMT2A at 2 A resolution Descriptor: CHLORIDE ION, SODIUM ION, SULFATE ION, ... Authors: Davydova, E, Janowski, R, Witzenberger, M, Niessing, D. Deposit date: 2021-03-10 Release date: 2022-01-19 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.016 Å) Cite: Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death. Comput Struct Biotechnol J, 20, 2022
2XZ2	Crystal structure of CstF-50 homodimerization domain Descriptor: CSTF-50, ISOFORM B, DI(HYDROXYETHYL)ETHER, ... Authors: Moreno-Morcillo, M, Fribourg, S. Deposit date: 2010-11-22 Release date: 2011-01-26 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Hexameric Architecture of Cstf Supported by Cstf- 50 Homodimerization Domain Structure. RNA, 17, 2011
2C4B	Inhibitor cystine knot protein McoEeTI fused to the catalytically inactive barnase mutant H102A Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BARNASE MCOEETI FUSION, ... Authors: Niemann, H.H, Schmoldt, H.U, Wentzel, A, Kolmar, H, Heinz, D.W. Deposit date: 2005-10-18 Release date: 2005-11-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Barnase Fusion as a Tool to Determine the Crystal Structure of the Small Disulfide-Rich Protein Mcoeeti. J.Mol.Biol., 356, 2006
8KAK	Crystal structure of SpyCas9 in complex with sgRNA and 18nt target DNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025
8KAM	Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.91 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025
8KAL	Crystal structure of SpyCas9 in complex with sgRNA and 17nt target DNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025
8AXF	Crystal structure of FMV N bound to 42-mer ssRNA Descriptor: GLYCEROL, MAGNESIUM ION, Nucleocapsid protein, ... Authors: Izhaki-Tavor, L, Yechezkel, I, Dessau, M. Deposit date: 2022-08-31 Release date: 2023-04-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.54 Å) Cite: RNA Encapsulation Mode and Evolutionary Insights from the Crystal Structure of Emaravirus Nucleoprotein. Microbiol Spectr, 11, 2023
5H3U	Sm RNA bound to GEMIN5-WD Descriptor: GLYCEROL, Gem-associated protein 5, RNA (5'-R(*AP*AP*UP*UP*UP*UP*UP*GP*AP*C)-3') Authors: Bharath, S.R, Tang, X, Song, H. Deposit date: 2016-10-27 Release date: 2016-12-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.499 Å) Cite: Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
6OZM	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 10 min soak in 10 mM Mn2+ Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... Authors: Samara, N.L, Yang, W. Deposit date: 2019-05-15 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZN	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mn2+ Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... Authors: Samara, N.L, Yang, W. Deposit date: 2019-05-15 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZO	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 30 min soak in 10 mM Mn2+ Descriptor: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... Authors: Samara, N.L, Yang, W. Deposit date: 2019-05-15 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.235 Å) Cite: Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6H9X	Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Seryl)-Sulfamoyl)Adenosine Descriptor: 1,2-ETHANEDIOL, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CALCIUM ION, ... Authors: Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. Deposit date: 2018-08-06 Release date: 2019-05-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily. Eur.J.Med.Chem., 174, 2019
1A2P	BARNASE WILDTYPE STRUCTURE AT 1.5 ANGSTROMS RESOLUTION Descriptor: BARNASE, ZINC ION Authors: Martin, C, Richard, V, Salem, M, Hartley, R.W, Mauguen, Y. Deposit date: 1998-01-07 Release date: 1998-04-29 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Refinement and structural analysis of barnase at 1.5 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
3MDG	Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UUGUAU Descriptor: Cleavage and polyadenylation specificity factor subunit 5, GLYCEROL, RNA (5'-R(*UP*UP*GP*UP*AP*U)-3') Authors: Yang, Q, Gilmartin, G.M, Doublie, S. Deposit date: 2010-03-30 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing. Proc.Natl.Acad.Sci.USA, 107, 2010
3MDI	Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UGUAAA Descriptor: Cleavage and polyadenylation specificity factor subunit 5, GLYCEROL, RNA (5'-R(*UP*GP*UP*AP*AP*A)-3') Authors: Yang, Q, Gilmartin, G.M, Doublie, S. Deposit date: 2010-03-30 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing. Proc.Natl.Acad.Sci.USA, 107, 2010
5ID6	Structure of Cpf1/RNA Complex Descriptor: Cpf1, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3') Authors: Dong, D, Ren, K, Qiu, X, Wang, J, Huang, Z. Deposit date: 2016-02-24 Release date: 2016-04-27 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.382 Å) Cite: The crystal structure of Cpf1 in complex with CRISPR RNA Nature, 532, 2016

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