6H9X
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Seryl)-Sulfamoyl)Adenosine
Summary for 6H9X
Entry DOI | 10.2210/pdb6h9x/pdb |
Descriptor | Serine--tRNA ligase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | coil-coil, beta barrel, trna synthetase, complex, ligase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 49409.01 |
Authors | Pang, L.,De Graef, S.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2018-08-06, release date: 2019-05-15, Last modification date: 2024-01-17) |
Primary citation | De Ruysscher, D.,Pang, L.,De Graef, S.,Nautiyal, M.,De Borggraeve, W.M.,Rozenski, J.,Strelkov, S.V.,Weeks, S.D.,Van Aerschot, A. Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily. Eur.J.Med.Chem., 174:252-264, 2019 Cited by PubMed: 31048140DOI: 10.1016/j.ejmech.2019.04.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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