6OZM
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 10 min soak in 10 mM Mn2+
Summary for 6OZM
Entry DOI | 10.2210/pdb6ozm/pdb |
Descriptor | Endonuclease V, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), GLYCEROL, ... (7 entities in total) |
Functional Keywords | nucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase-rna complex, hydrolase/rna |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 71721.20 |
Authors | Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2024-03-13) |
Primary citation | Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W. Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76:44-, 2019 Cited by PubMed: 31444105DOI: 10.1016/j.molcel.2019.06.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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