3MDG

Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UUGUAU

Summary for 3MDG

• Entry DOI: 10.2210/pdb3mdg/pdb
• Related: 2Cl3 2j8q 3BAP 3BHO 3MDI
• Descriptor: Cleavage and polyadenylation specificity factor subunit 5, RNA (5'-R(*UP*UP*GP*UP*AP*U)-3'), GLYCEROL, ... (4 entities in total)
• Functional Keywords: cpsf5, cf im, mrna processing, cleavage factor, nudix protein, protein-rna complex, rna binding protein, rna binding-rna complex, rna binding/rna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O43809
• Total number of polymer chains: 3
• Total formula weight: 54648.88

Authors

Yang, Q.,Gilmartin, G.M.,Doublie, S. (deposition date: 2010-03-30, release date: 2010-06-02, Last modification date: 2023-09-06)

• Primary citation: Yang, Q.,Gilmartin, G.M.,Doublie, S.; Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing.; Proc.Natl.Acad.Sci.USA, 107:10062-10067, 2010; PubMed: 20479262; DOI: 10.1073/pnas.1000848107

Experimental method

X-RAY DIFFRACTION (2.22 Å)