6OZN

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mn2+

Summary for 6OZN

• Entry DOI: 10.2210/pdb6ozn/pdb
• Descriptor: Endonuclease V, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), MANGANESE (II) ION, ... (9 entities in total)
• Functional Keywords: nucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase-rna complex, hydrolase/rna
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 4
• Total formula weight: 72636.65

Authors

Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2024-03-13)

• Primary citation: Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W.; Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.; Mol.Cell, 76:44-, 2019; PubMed: 31444105; DOI: 10.1016/j.molcel.2019.06.046

Experimental method

X-RAY DIFFRACTION (1.9 Å)