6OZN

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004519	molecular_function	endonuclease activity
A	0006281	biological_process	DNA repair
B	0004519	molecular_function	endonuclease activity
B	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 301

Chain	Residue
A	ASP52
A	ASP240
A	HOH422
C	U12
C	HOH201
C	HOH210

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 302

Chain	Residue
A	HOH417
C	A11
C	U12
A	ASP52
A	ASP126
A	HOH410

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MN A 303

Chain	Residue
A	LEU45
A	GLN46
A	HOH404
A	HOH430
A	HOH438

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 304

Chain	Residue
A	TYR79
A	GLU80
A	LYS114
A	HOH453

---

site_id	AC5
Number of Residues	3
Details	binding site for residue PGE A 305

Chain	Residue
A	HIS225
A	HIS226
A	ARG229

---

site_id	AC6
Number of Residues	2
Details	binding site for residue EDO A 306

Chain	Residue
A	ASP201
A	HIS202

---

site_id	AC7
Number of Residues	2
Details	binding site for residue EDO A 307

Chain	Residue
A	GLN133
A	PG4312

---

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO A 308

Chain	Residue
A	ASP39
A	SER41
A	SER43
B	GLN112
B	GLU113

---

site_id	AC9
Number of Residues	4
Details	binding site for residue EDO A 309

Chain	Residue
A	LYS170
A	ILE173
A	VAL174
A	HOH473

---

site_id	AD1
Number of Residues	9
Details	binding site for residue P6G A 310

Chain	Residue
A	ARG27
A	VAL144
A	LEU145
A	THR146
A	GLU147
A	GLU171
B	ASP32
B	ALA35
B	ARG38

---

site_id	AD2
Number of Residues	6
Details	binding site for residue PG4 A 311

Chain	Residue
A	GLU34
A	ALA35
A	ARG38
B	ARG27
B	LEU145
B	THR146

---

site_id	AD3
Number of Residues	4
Details	binding site for residue PG4 A 312

Chain	Residue
A	LYS25
A	VAL28
A	EDO307
A	HOH405

---

site_id	AD4
Number of Residues	6
Details	binding site for residue MN B 301

Chain	Residue
B	ASP52
B	ASP240
B	HOH435
D	U12
D	HOH208
D	HOH217

---

site_id	AD5
Number of Residues	6
Details	binding site for residue MN B 302

Chain	Residue
B	LEU45
B	GLN46
B	MN303
B	HOH405
B	HOH412
B	HOH422

---

site_id	AD6
Number of Residues	4
Details	binding site for residue MN B 303

Chain	Residue
B	GLN46
B	TYR72
B	MN302
B	HOH405

---

site_id	AD7
Number of Residues	3
Details	binding site for residue PGE B 304

Chain	Residue
B	PRO73
B	HIS226
B	HOH441

---

site_id	AD8
Number of Residues	7
Details	binding site for residue MN C 101

Chain	Residue
A	HOH414
C	U12
C	A13
C	HOH201
C	HOH203
C	HOH209
C	HOH215

---

site_id	AD9
Number of Residues	3
Details	binding site for residue GOL C 102

Chain	Residue
C	A17
C	U18
C	G19

---

site_id	AE1
Number of Residues	6
Details	binding site for residue MN D 101

Chain	Residue
B	ASP52
B	ASP126
B	HOH408
B	HOH415
D	A11
D	U12

---

site_id	AE2
Number of Residues	6
Details	binding site for residue MN D 102

Chain	Residue
D	U12
D	A13
D	HOH207
D	HOH208
D	HOH210
D	HOH213

---

site_id	AE3
Number of Residues	3
Details	binding site for residue MN D 103

Chain	Residue
D	HOH209
D	HOH203
D	HOH205

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Site: {"description":"Interaction with target DNA","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---