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8JZC
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Crystal structure of Geobacillus stearothermophilus NarJ
Descriptor: Nitrate reductase molybdenum cofactor assembly chaperone
Authors:Song, W.S, Kim, J.H, Namgung, B, Cho, H.Y, Oh, H.B, Yoon, S.I.
Deposit date:2023-07-05
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Complementary hydrophobic interaction of the redox enzyme maturation protein NarJ with the signal peptide of the respiratory nitrate reductase NarG.
Int.J.Biol.Macromol., 262, 2024
8JZ8
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BU of 8jz8 by Molmil
Subatomic structure of orthorhombic thaumatin at 0.89 Angstroms
Descriptor: DI(HYDROXYETHYL)ETHER, Thaumatin I
Authors:Masuda, T, Suzuki, M, Yamasaki, M, Mikami, B.
Deposit date:2023-07-04
Release date:2024-05-15
Method:X-RAY DIFFRACTION (0.89 Å)
Cite:Subatomic structure of orthorhombic thaumatin at 0.89 angstrom reveals that highly flexible conformations are crucial for thaumatin sweetness.
Biochem.Biophys.Res.Commun., 703, 2024
8JZ7
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BU of 8jz7 by Molmil
Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein
Descriptor: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
Deposit date:2023-07-04
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2.
Signal Transduct Target Ther, 8, 2023
8JZ1
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BU of 8jz1 by Molmil
Crystal structure of a single-chain monellin mutant C41V
Descriptor: Monellin chain B,Monellin chain A
Authors:Yasui, N, Ohnuma, K, Yamashita, A.
Deposit date:2023-07-04
Release date:2023-10-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.239 Å)
Cite:Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin.
Protein J., 42, 2023
8JZ0
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BU of 8jz0 by Molmil
Crystal structure of a single-chain monellin mutant C41A
Descriptor: Monellin chain B,Monellin chain A
Authors:Yasui, N, Ohnuma, K, Yamashita, A.
Deposit date:2023-07-04
Release date:2023-10-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.229 Å)
Cite:Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin.
Protein J., 42, 2023
8JYR
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BU of 8jyr by Molmil
Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H2Mab-119 VH-CH1, H2Mab-119 light chain, ...
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
8JYQ
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BU of 8jyq by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
Descriptor: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide
Authors:Arimori, T, Takagi, J.
Deposit date:2023-07-03
Release date:2024-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
8JYP
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BU of 8jyp by Molmil
Structure of SARS-CoV-2 XBB.1.5 spike RBD in complex with ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T.
Deposit date:2023-07-03
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
To Be Published
8JYO
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BU of 8jyo by Molmil
Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (2-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T.
Deposit date:2023-07-03
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
To Be Published
8JYN
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BU of 8jyn by Molmil
Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (1-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T.
Deposit date:2023-07-03
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
To Be Published
8JYM
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BU of 8jym by Molmil
Structure of the SARS-CoV-2 XBB.1.5 spike glycoprotein (closed state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T.
Deposit date:2023-07-03
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
To Be Published
8JYK
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BU of 8jyk by Molmil
Structure of the SARS-CoV-2 XBB.1.5 spike glycoprotein (closed state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T.
Deposit date:2023-07-03
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Virological characteristics of the SARS-CoV-2 XBB.1.5 variant
To Be Published
8JY8
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BU of 8jy8 by Molmil
Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidine
Descriptor: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Aquaglyceroporin 2
Authors:Chen, W, Wang, C.
Deposit date:2023-07-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
8JY7
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BU of 8jy7 by Molmil
Structure of the TbAQP2 in the apo conformation
Descriptor: Aquaglyceroporin 2
Authors:Chen, W, Wang, C.
Deposit date:2023-07-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
8JY6
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BU of 8jy6 by Molmil
Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
Descriptor: Aquaglyceroporin 2, [(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
Authors:Chen, W, Wang, C.
Deposit date:2023-07-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
8JY5
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BU of 8jy5 by Molmil
Cryo-EM structure of human ABC transporter ABCC2 in apo" state
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-03
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JY4
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BU of 8jy4 by Molmil
Cryo-EM structure of human ABC transporter ABCC2 in apo' state
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-02
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JXU
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BU of 8jxu by Molmil
Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ...
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-01
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JXQ
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BU of 8jxq by Molmil
Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2
Descriptor: 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-01
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JXN
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BU of 8jxn by Molmil
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state with MCoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ...
Authors:Liu, D.S, Su, J.Y, Tian, X.Y.
Deposit date:2023-06-30
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state with substrate
To Be Published
8JXM
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BU of 8jxm by Molmil
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state with MCoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ...
Authors:Liu, D.S, Su, J.Y, Tian, X.Y.
Deposit date:2023-06-30
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Human 3-methylcrotonyl-CoA carboxylase in
To Be Published
8JXL
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BU of 8jxl by Molmil
Human 3-methylcrotonyl-CoA carboxylase in MCCU state with MCoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ...
Authors:Liu, D.S, Su, J.Y, Tian, X.Y.
Deposit date:2023-06-30
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Human 3-methylcrotonyl-CoA carboxylase in BCCP-BCS state with substrate
To Be Published
8JXJ
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BU of 8jxj by Molmil
rat megalin RAP complex leg
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LDL receptor related protein 2, ...
Authors:Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A.
Deposit date:2023-06-30
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
8JXI
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BU of 8jxi by Molmil
rat megalin RAP complex wingB
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A.
Deposit date:2023-06-30
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
8JXH
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BU of 8jxh by Molmil
rat megalin RAP complex wingA
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A.
Deposit date:2023-06-30
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024

223532

數據於2024-08-07公開中

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