7OWY
 
 | | Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 3 minutes showing a peroxide anion as bridging species of iron ions in the ferroxidase site | | Descriptor: | CHLORIDE ION, FE (II) ION, Ferritin, ... | | Authors: | Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S. | | Deposit date: | 2021-06-21 | | Release date: | 2021-10-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
|
|
8XYC
 | |
9G5K
 | |
7XZU
 | | Crystal structure of Ricin A chain bound with (2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)-L-phenylalanine | | Descriptor: | (2S)-2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]-3-phenyl-propanoic acid, Ricin A chain, SULFATE ION | | Authors: | Goto, M, Higashi, S, Ohba, T, Kawata, R, Nagatsu, K, Suzuki, S, Saito, R. | | Deposit date: | 2022-06-03 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket.
Biochem.Biophys.Res.Commun., 627, 2022
|
|
9BER
 | | Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Gorman, J, Kwong, P.D. | | Deposit date: | 2024-04-16 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Cell Rep, 43, 2024
|
|
7M30
 | |
9IMA
 | | Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab | | Descriptor: | CHOLESTEROL, G-protein coupled receptor family C group 5 member D, Talquetamab Fab (anti-GPRC5D) Heavy chain, ... | | Authors: | Jeong, J, Shin, J, Park, J, Cho, Y. | | Deposit date: | 2024-07-02 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma.
J.Mol.Biol., 436, 2024
|
|
9F1T
 | |
7Y08
 | | Crystal structure of Ricin A chain bound with (2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanine | | Descriptor: | N-[(2-amino-4-oxo-1,4-dihydropteridin-7-yl)carbonyl]glycyl-L-phenylalanine, Ricin A chain, SULFATE ION | | Authors: | Goto, M, Higashi, S, Ohba, T, Kawata, R, Nagatsu, K, Suzuki, S, Saito, R. | | Deposit date: | 2022-06-03 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket.
Biochem.Biophys.Res.Commun., 627, 2022
|
|
8YHZ
 | |
9BKR
 | | Crystal structure of the Human TRIP12 WWE domain (isoform 2) in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Isoform 2 of E3 ubiquitin-protein ligase TRIP12, UNKNOWN ATOM OR ION | | Authors: | Kimani, S, Dong, A, Li, Y, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | Deposit date: | 2024-04-29 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of the Human TRIP12 WWE domain (isoform 2) in complex with ATP
To be published
|
|
9F37
 | |
9CG7
 | | 70S initiation complex (tRNA-fMet M1 + AUG start codon) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Mattingly, J.M, Nguyen, H.A, Dunham, C.M. | | Deposit date: | 2024-06-28 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
|
|
9EM6
 | |
9CIA
 | | T cell receptor complex | | Descriptor: | CHOLESTEROL, T cell receptor delta constant, T cell receptor gamma constant 1, ... | | Authors: | Gully, B.S, Rossjohn, J. | | Deposit date: | 2024-07-03 | | Release date: | 2024-07-31 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | T cell receptor complex
To Be Published
|
|
6IK7
 | | Crystal structure of tomato beta-galactosidase (TBG) 4 in complex with beta-1,3-galactobiose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | | Authors: | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | | Deposit date: | 2018-10-15 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation.
Planta, 252, 2020
|
|
9GDL
 | |
9FJ3
 | | Structure of ubiquitin bound of coiled-coil UIM form 2 | | Descriptor: | 3-[1-(2-oxidanylideneethyl)-1,2,3-triazol-4-yl]propanal, GLU-GLN-GLU-ILE-GLU-GLU-LEU-GLU-ILE-GLU-ILE-ALA-ILE-LEU-LEU-SER-GLU-ILE-GLU-GLY, LYS-GLN-LYS-ILE-ALA-ALA-LEU-LYS-TYR-LYS-ILE-ALA-ALA-LEU-LYS-GLN-LYS-ILE, ... | | Authors: | Paredes Vergara, P, Huang, D.T. | | Deposit date: | 2024-05-30 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | An engineered ubiquitin binding coiled coil peptide.
Chem Sci, 15, 2024
|
|
9C4D
 | |
9C82
 | | Structure of human ULK1C:PI3KC3-C1 supercomplex | | Descriptor: | Beclin 1-associated autophagy-related key regulator, Beclin-1, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | | Authors: | Chen, M, Hurley, J.H. | | Deposit date: | 2024-06-11 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (6.84 Å) | | Cite: | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
|
|
9B8T
 | | Human polymerase epsilon bound to PCNA and DNA in the nucleotide bound state | | Descriptor: | DNA polymerase epsilon catalytic subunit, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Wang, F, He, Q, Li, H. | | Deposit date: | 2024-03-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structures of the human leading strand Pol epsilon-PCNA holoenzyme.
Nat Commun, 15, 2024
|
|
9FJK
 | | Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6 | | Descriptor: | K501SP6 Fv Heavy Chain, K501SP6 Fv Light Chain, Spike glycoprotein,Fibritin | | Authors: | Bjoernsson, K.H, Walker, M.R, Raghavan, S.S.R, Ward, A.B, Barfod, L.K. | | Deposit date: | 2024-05-31 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6
To Be Published
|
|
9GE1
 | |
9FPZ
 | | Human NatA-MAP2 80S ribosome complex | | Descriptor: | 28S rRNA, 5.8S rRNA (58-MER), 60S ribosomal protein L19, ... | | Authors: | Klein, M.A, Wild, K, Sinning, I. | | Deposit date: | 2024-06-14 | | Release date: | 2024-07-03 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome.
Nat Commun, 15, 2024
|
|
4Y1A
 | | immune complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FS17_alpha, FS17_beta, ... | | Authors: | Beringer, D.X, Vivian, J.P, Reid, H.H, Rossjohn, J. | | Deposit date: | 2015-02-07 | | Release date: | 2015-09-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Nat.Immunol., 16, 2015
|
|
