7OWY

Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 3 minutes showing a peroxide anion as bridging species of iron ions in the ferroxidase site

Summary for 7OWY

• Entry DOI: 10.2210/pdb7owy/pdb
• Related: 7O63 7O64 7O65 7O66 7O67 7O68 7O69 7O6A 7O6C 7O6D
• Descriptor: Ferritin, mitochondrial, FE (II) ION, HYDROGEN PEROXIDE, ... (6 entities in total)
• Functional Keywords: human mitochondrial ferritin, hmtf, time-controlled iron loading, ferroxidase site, peroxide anion, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 21834.61

Authors

Pozzi, C.,Ciambellotti, S.,Tassone, G.,Turano, P.,Mangani, S. (deposition date: 2021-06-21, release date: 2021-10-13, Last modification date: 2024-01-31)

• Primary citation: Ciambellotti, S.,Pratesi, A.,Tassone, G.,Turano, P.,Mangani, S.,Pozzi, C.; Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.; Chemistry, 27:14690-14701, 2021; PubMed: 34343376; DOI: 10.1002/chem.202102270

Experimental method

X-RAY DIFFRACTION (1.55 Å)