7C45
| |
7C42
| |
5UDZ
| |
3TS2
| Mouse Lin28A in complex with let-7g microRNA pre-element | Descriptor: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*CP*UP*AP*UP*GP*AP*UP*AP*CP*CP*AP*CP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION | Authors: | Nam, Y, Sliz, P. | Deposit date: | 2011-09-11 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
|
|
7C4B
| The crystal structure of Trypanosoma brucei RNase D : UMP complex | Descriptor: | CCHC-type domain-containing protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Gao, Y.Q, Gan, J.H. | Deposit date: | 2020-05-15 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021
|
|
7C47
| The crystal structure of Trypanosoma brucei RNase D : CMP complex | Descriptor: | CCHC-type domain-containing protein, CYTIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Gao, Y.Q, Gan, J.H. | Deposit date: | 2020-05-15 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021
|
|
7C4C
| |
5W0M
| Structure of human TUT7 catalytic module (CM) in complex with U5 RNA | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
|
|
7C43
| |
5W0O
| |
5W0N
| Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
|
|
8E3I
| CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ... | Authors: | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | Deposit date: | 2022-08-17 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF. Rna, 28, 2022
|
|
5W0B
| Structure of human TUT7 catalytic module (CM) | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-30 | Release date: | 2017-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.614 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
|
|
8E3Q
| CRYO-EM STRUCTURE OF the human MPSF | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, ZINC ION, ... | Authors: | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | Deposit date: | 2022-08-17 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF. Rna, 28, 2022
|
|
3NYB
| |
5O2U
| Llama VHH in complex with p24 | Descriptor: | Capsid protein p24, VHH 59H10 | Authors: | Caillat, C, Verrips, T, Weissenhorn, W. | Deposit date: | 2017-05-22 | Release date: | 2017-06-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights. ACS Infect Dis, 3, 2017
|
|
3TS0
| Mouse Lin28A in complex with let-7f-1 microRNA pre-element | Descriptor: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*AP*GP*UP*GP*AP*UP*UP*UP*UP*AP*CP*CP*CP*UP*GP*GP*AP*G)-3'), ZINC ION | Authors: | Nam, Y, Sliz, P. | Deposit date: | 2011-09-11 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.763 Å) | Cite: | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
|
|
8R8R
| Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ... | Authors: | Todesca, S, Sandmeir, F, Keidel, A, Conti, E. | Deposit date: | 2023-11-29 | Release date: | 2024-04-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Molecular basis of human poly(A) polymerase recruitment by mPSF. Rna, 30, 2024
|
|
3TRZ
| Mouse Lin28A in complex with let-7d microRNA pre-element | Descriptor: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*CP*AP*GP*GP*GP*AP*UP*UP*UP*UP*GP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION | Authors: | Nam, Y, Sliz, P. | Deposit date: | 2011-09-11 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
|
|
6URG
| Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ... | Authors: | Sun, Y, Zhang, Y, Walz, T, Tong, L. | Deposit date: | 2019-10-23 | Release date: | 2019-11-27 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
|
|
7VPX
| The cryo-EM structure of the human pre-A complex | Descriptor: | 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-10-18 | Release date: | 2023-05-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
|
|
7W5Z
| Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ... | Authors: | Zhou, L, Maldonado, M, Padavannil, A, Letts, J. | Deposit date: | 2021-11-30 | Release date: | 2022-04-06 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
|
|
8C9M
| HERV-K Gag immature lattice | Descriptor: | Gag protein | Authors: | Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P. | Deposit date: | 2023-01-23 | Release date: | 2023-02-01 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular architecture and conservation of an immature human endogenous retrovirus. Biorxiv, 2023
|
|
6DNH
| Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ... | Authors: | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | Deposit date: | 2018-06-06 | Release date: | 2018-06-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7Z52
| Human NEXT dimer - focused reconstruction of the single MTR4 | Descriptor: | Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ... | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | Deposit date: | 2022-03-07 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Mol.Cell, 82, 2022
|
|