8E3Q

CRYO-EM STRUCTURE OF the human MPSF

Summary for 8E3Q

• Entry DOI: 10.2210/pdb8e3q/pdb
• EMDB information: 27870
• Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, pre-mRNA 3' end processing protein WDR33, ... (4 entities in total)
• Functional Keywords: mrna, 3'processing, polyadenylation, cpsf, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 254697.74

Authors

Gutierrez, P.A.,Wei, J.,Sun, Y.,Tong, L. (deposition date: 2022-08-17, release date: 2023-01-18)

• Primary citation: Gutierrez, P.A.,Wei, J.,Sun, Y.,Tong, L.; Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.; Rna, 28:1534-1541, 2022; PubMed: 36130077; DOI: 10.1261/rna.079322.122

Experimental method

ELECTRON MICROSCOPY (2.68 Å)