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8E3Q

CRYO-EM STRUCTURE OF the human MPSF

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cleavage and polyadenylation specificity factor subunit 1polymer1443161074.21UniProt (Q10570)
Pfam (PF10433)
Pfam (PF23726)
Pfam (PF03178)
Homo sapiens (human)Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit
2B
(C)
Cleavage and polyadenylation specificity factor subunit 4polymer24527646.11UniProt (O95639)
Pfam (PF15663)
Pfam (PF00642)
Pfam (PF00098)
Homo sapiens (human)Cleavage and polyadenylation specificity factor 30 kDa subunit, CPSF 30 kDa subunit, NS1 effector domain-binding protein 1, Neb-1, No arches homolog
3C
(B)
pre-mRNA 3' end processing protein WDR33polymer57265912.01UniProt (Q9C0J8)
Pfam (PF00400)
Homo sapiens (human)WD repeat-containing protein 33,WD repeat-containing protein of 146 kDa
4D
(C)
ZINC IONnon-polymer65.41Chemie (ZN)
PubChem (32051)
Sequence modifications
C: 1 - 244 (UniProt: O95639)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight254632.3
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight254697.7
*Water molecules are not included.

259693

PDB entries from 2026-09-16

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