PDB: 8861 resultsInfo pagesStatus searchChemie searchBIRD

---

8INK	human nuclear pre-60S ribosomal particle - State D Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-03-10 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IE3	human nuclear pre-60S ribosomal particle - State E Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-15 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IDY	human nuclear pre-60S ribosomal particle - State F Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IPD	human nuclear pre-60S ribosomal particle - State C Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-03-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IDT	human nuclear pre-60S ribosomal particle - State G Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
5W6V	The Structure of human Argonaute-1 in complex with the hook motif of human GW182 Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein Authors: Elkayam, E, Faehnle, C.R, Joshua-Tor, L. Deposit date: 2017-06-17 Release date: 2017-07-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.828 Å) Cite: Multivalent Recruitment of Human Argonaute by GW182. Mol. Cell, 67, 2017
4V6X	Structure of the human 80S ribosome Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. Deposit date: 2013-02-27 Release date: 2014-07-09 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (5 Å) Cite: Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
6LQS	Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
4M5U	5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease Descriptor: 5-(4-fluorophenyl)-3-hydroxy-6-[4-(1H-tetrazol-5-yl)phenyl]pyridin-2(1H)-one, MANGANESE (II) ION, Polymerase PA, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Phenyl substituted 3-hydroxypyridin-2(1H)-ones: inhibitors of influenza A endonuclease. Bioorg.Med.Chem., 21, 2013
8Y7E	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part Descriptor: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. Deposit date: 2024-02-04 Release date: 2024-03-13 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.66 Å) Cite: Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
8H6E	Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. Deposit date: 2022-10-17 Release date: 2024-05-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6J	Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. Deposit date: 2022-10-18 Release date: 2024-05-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8QO9	Cryo-EM structure of a human spliceosomal B complex protomer Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. Deposit date: 2023-09-28 Release date: 2024-01-24 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (5.29 Å) Cite: Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
8H6K	Cryo-EM structure of human exon-defined spliceosome in the mature B state. Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. Deposit date: 2022-10-18 Release date: 2024-05-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6L	Cryo-EM structure of human exon-defined spliceosome in the early B state. Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. Deposit date: 2022-10-18 Release date: 2024-05-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8YOP	Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Li, X, Wang, M, Denk, T, Cheng, J. Deposit date: 2024-03-13 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8YOO	Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Li, X, Wang, M, Denk, T, Cheng, J. Deposit date: 2024-03-13 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (2 Å) Cite: Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
7NV1	Human Pol Kappa holoenzyme with Ub-PCNA Descriptor: DNA Primer, DNA Template, DNA polymerase kappa, ... Authors: Lancey, C, De Biasio, A, Hamdan, S.M. Deposit date: 2021-03-15 Release date: 2021-11-03 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (6.4 Å) Cite: Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
7NV0	Human Pol Kappa holoenzyme with wt PCNA Descriptor: DNA Primer, DNA Template, DNA polymerase kappa, ... Authors: Lancey, C, De Biasio, A, Hamdan, S.M. Deposit date: 2021-03-15 Release date: 2021-11-10 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
8FL2	Human nuclear pre-60S ribosomal subunit (State I1) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLA	Human nuclear pre-60S ribosomal subunit (State K1) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (2.63 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL4	Human nuclear pre-60S ribosomal subunit (State I3) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLD	Human nuclear pre-60S ribosomal subunit (State L1) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL3	Human nuclear pre-60S ribosomal subunit (State I2) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL6	Human nuclear pre-60S ribosomal subunit (State J1) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023

<87888990919293949596979899100101102>