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7YMD
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BU of 7ymd by Molmil
Cryo-EM structure of Nse1/3/4
Descriptor: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosomes element 1
Authors:Qian, L, Jun, Z, Zhenguo, C, Wang, L.
Deposit date:2022-07-28
Release date:2024-01-31
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.176 Å)
Cite:Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
7FJ1
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BU of 7fj1 by Molmil
Cryo-EM structure of pseudorabies virus C-capsid
Descriptor: Capsid vertex component 1, DNA packaging tegument protein UL25, Major capsid protein, ...
Authors:Zheng, Q, Li, S, Zha, Z, Sun, H.
Deposit date:2021-08-02
Release date:2022-06-22
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Structures of pseudorabies virus capsids.
Nat Commun, 13, 2022
1XPR
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BU of 1xpr by Molmil
Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-formylbicyclomycin (FB)
Descriptor: 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3', 5A-FORMYLBICYCLOMYCIN, MAGNESIUM ION, ...
Authors:Skordalakes, E, Brogan, A.P, Park, B.S, Kohn, H, Berger, J.M.
Deposit date:2004-10-09
Release date:2004-11-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural mechanism of inhibition of the rho transcription termination factor by the antibiotic bicyclomycin
Structure, 13, 2005
2B5M
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BU of 2b5m by Molmil
Crystal Structure of DDB1
Descriptor: damage-specific DNA binding protein 1
Authors:Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
1UE2
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BU of 1ue2 by Molmil
Crystal structure of d(GC38GAAAGCT)
Descriptor: 5'-D(*GP*(C38)P*GP*AP*AP*AP*GP*CP*T)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanaba, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
1UB8
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BU of 1ub8 by Molmil
Crystal structure of d(GCGAAGC), bending duplex with a bulge-in residue
Descriptor: 5'-D(*GP*CP*GP*AP*AP*GP*C)-3', COBALT HEXAMMINE(III)
Authors:Sunami, T, Kondo, J, Hirao, I, Watanabe, K, Miura, K, Takenaka, A.
Deposit date:2003-03-31
Release date:2004-03-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of d(GCGAAGC) and d(GCGAAAGC) (tetragonal form): a switching of partners of the sheared G.A pairs to form a functional G.AxA.G crossing.
Acta Crystallogr.,Sect.D, 60, 2004
1F3U
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BU of 1f3u by Molmil
CRYSTAL STRUCTURE OF THE RAP30/74 INTERACTION DOMAINS OF HUMAN TFIIF
Descriptor: TRANSCRIPTION INITIATION FACTOR IIF, ALPHA SUBUNIT, BETA SUBUNIT
Authors:Gaiser, F, Tan, S, Richmond, T.J.
Deposit date:2000-06-06
Release date:2000-10-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 A resolution.
J.Mol.Biol., 302, 2000
4MQ3
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BU of 4mq3 by Molmil
The 1.1 Angstrom Structure of Catalytic Core Domain of FIV Integrase
Descriptor: Integrase
Authors:Galilee, M, Alian, A.
Deposit date:2013-09-15
Release date:2014-09-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Identification of phe187 as a crucial dimerization determinant facilitates crystallization of a monomeric retroviral integrase core domain.
Structure, 22, 2014
4LEU
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BU of 4leu by Molmil
Crystal Structure of THA8-like protein from Arabidopsis thaliana
Descriptor: Pentatricopeptide repeat-containing protein At3g46870
Authors:Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Kang, Y, Melcher, K, Zhu, J.K, Xu, H.E.
Deposit date:2013-06-26
Release date:2013-09-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a PLS-class Pentatricopeptide Repeat Protein Provides Insights into Mechanism of RNA Recognition.
J.Biol.Chem., 288, 2013
1UE4
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BU of 1ue4 by Molmil
Crystal structure of d(GCGAAAGC)
Descriptor: 5'-D(*GP*CP*GP*AP*AP*AP*GP*C)-3', MAGNESIUM ION
Authors:Sunami, T, Kondo, J, Hirao, I, Watanabe, K, Miura, K, Takenaka, A.
Deposit date:2003-05-09
Release date:2004-03-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of d(GCGAAGC) and d(GCGAAAGC) (tetragonal form): a switching of partners of the sheared G.A pairs to form a functional G.AxA.G crossing.
Acta Crystallogr.,Sect.D, 60, 2004
1U01
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BU of 1u01 by Molmil
High resolution NMR structure of 5-d(GCGT*GCG)-3/5-d(CGCACGC)-3 (T*represents a cyclohexenyl nucleotide)
Descriptor: 5'-D(*CP*GP*CP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*(XTR)P*GP*CP*G)-3'
Authors:Nauwelaerts, K, Lescrinier, E, Sclep, G, Herdewijn, P.
Deposit date:2004-07-12
Release date:2005-05-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides.
Nucleic Acids Res., 33, 2005
1UE3
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BU of 1ue3 by Molmil
Crystal structure of d(GCGAAAGC) containing hexaamminecobalt
Descriptor: 5'-D(*GP*CP*GP*AP*AP*AP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanabe, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
4ID1
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BU of 4id1 by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
Descriptor: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Gag-Pol polyprotein, SULFATE ION
Authors:Feng, L, Kvaratskhelia, M.
Deposit date:2012-12-11
Release date:2013-05-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Proc.Natl.Acad.Sci.USA, 110, 2013
1HAR
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BU of 1har by Molmil
2.2 ANGSTROMS RESOLUTION STRUCTURE OF THE AMINO-TERMINAL HALF OF HIV-1 REVERSE TRANSCRIPTASE (FINGERS AND PALM SUBDOMAINS)
Descriptor: HIV-1 REVERSE TRANSCRIPTASE (FINGERS AND PALM SUBDOMAINS)
Authors:Unge, T, Knight, S, Strandberg, B.
Deposit date:1994-10-28
Release date:1995-04-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:2.2 A resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains).
Structure, 2, 1994
5W45
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BU of 5w45 by Molmil
Crystal structure of APOBEC3H
Descriptor: APOBEC3H, ZINC ION
Authors:Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S.
Deposit date:2017-06-09
Release date:2018-03-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.
Sci Rep, 8, 2018
1E2F
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BU of 1e2f by Molmil
Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate and a magnesium-ion
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Ostermann, N, Schlichting, I, Brundiers, R, Konrad, M, Reinstein, J, Veit, T, Goody, R.S, Lavie, A.
Deposit date:2000-05-22
Release date:2001-05-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Insights Into the Phosphoryltransfer Mechanism of Human Thymidylate Kinase Gained from Crystal Structures of Enzyme Complexes Along the Reaction Coordinate
Structure, 8, 2000
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
Descriptor: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
Authors:Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
Deposit date:2013-11-01
Release date:2014-04-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
4N0L
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BU of 4n0l by Molmil
Methanopyrus kandleri Csm3 crystal structure
Descriptor: Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION
Authors:Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L.
Deposit date:2013-10-02
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3.
Rna Biol., 10, 2013
4HEJ
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BU of 4hej by Molmil
Discovery of Selective and Potent Inhibitors of Gram-positive Bacterial Thymidylate Kinase (TMK): Compund 16
Descriptor: 5-methyl-1-[(3S)-1-{3-[3-(trifluoromethyl)phenoxy]benzyl}piperidin-3-yl]pyrimidine-2,4(1H,3H)-dione, Thymidylate kinase
Authors:Martinez-Botella, G, Breen, J, Duffy, J, Dumas, J, Geng, B, Gowers, I, Green, O, Guler, S, Hentemann, M, Hernandez-Juan, F, Joseph-McCarthy, D, Kawatkar, S, Larsen, N, Lazari, O, Loch, J, Macritchie, J.
Deposit date:2012-10-03
Release date:2012-10-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK).
J.Med.Chem., 55, 2012
4NJC
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BU of 4njc by Molmil
RNA Polymerase interacting protein YkzG from Geobacillus stearothermophilus
Descriptor: Geobacillus stearothermophilus YkzG
Authors:Keller, A.N, Lewis, P.J.
Deposit date:2013-11-09
Release date:2014-08-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:epsilon, a New Subunit of RNA Polymerase Found in Gram-Positive Bacteria
J.Bacteriol., 196, 2014
1Y98
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BU of 1y98 by Molmil
Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
Authors:Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
Deposit date:2004-12-14
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
4N7R
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BU of 4n7r by Molmil
Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its binding protein
Descriptor: Genomic DNA, chromosome 3, P1 clone: MXL8, ...
Authors:Zhao, A, Fang, Y, Lin, Y, Gong, W, Liu, L.
Deposit date:2013-10-16
Release date:2014-05-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein
Proc.Natl.Acad.Sci.USA, 111, 2014
5YY9
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BU of 5yy9 by Molmil
Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3
Descriptor: E3 ubiquitin-protein ligase UHRF1, Ligase 1
Authors:Kori, S, Defossez, P.A, Arita, K.
Deposit date:2017-12-08
Release date:2018-12-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.653 Å)
Cite:Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.
Structure, 27, 2019
5YYA
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BU of 5yya by Molmil
Crystal structure of Tandem Tudor Domain of human UHRF1
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, SULFATE ION
Authors:Kori, S, Defossez, P.A, Arita, K.
Deposit date:2017-12-08
Release date:2018-12-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.
Structure, 27, 2019
4I1A
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BU of 4i1a by Molmil
Crystal Structure of the Apo Form of RapI
Descriptor: CHLORIDE ION, Response regulator aspartate phosphatase I
Authors:Parashar, V, Jeffrey, P.D, Neiditch, M.B.
Deposit date:2012-11-20
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.443 Å)
Cite:Conformational change-induced repeat domain expansion regulates rap phosphatase quorum-sensing signal receptors.
Plos Biol., 11, 2013

227344

数据于2024-11-13公开中

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