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1E2F

Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate and a magnesium-ion

Summary for 1E2F
Entry DOI10.2210/pdb1e2f/pdb
Related1E2D 1E2E 1E2G 1E2Q 1E98 1E99 1E9A 1E9B 1E9C 1E9D 1E9E 1E9F 1NMX 1NMY 1NMZ 1NN0 1NN1 1NN3 1NN5 2XX3
DescriptorTHYMIDYLATE KINASE, THYMIDINE-5'-PHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywordstransferase, treansferase, p-loop
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight25356.75
Authors
Ostermann, N.,Schlichting, I.,Brundiers, R.,Konrad, M.,Reinstein, J.,Veit, T.,Goody, R.S.,Lavie, A. (deposition date: 2000-05-22, release date: 2001-05-17, Last modification date: 2019-07-24)
Primary citationOstermann, N.,Schlichting, I.,Brundiers, R.,Konrad, M.,Reinstein, J.,Veit, T.,Goody, R.S.,Lavie, A.
Insights Into the Phosphoryltransfer Mechanism of Human Thymidylate Kinase Gained from Crystal Structures of Enzyme Complexes Along the Reaction Coordinate
Structure, 8:629-, 2000
Cited by
PubMed: 10873853
DOI: 10.1016/S0969-2126(00)00149-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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