2HYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hyu by Molmil](/molmil-images/mine/2hyu) | Human Annexin A2 with heparin tetrasaccharide bound | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Annexin A2, CALCIUM ION | Authors: | Shao, C, Head, J.F, Seaton, B.A. | Deposit date: | 2006-08-07 | Release date: | 2006-09-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2. J.Biol.Chem., 281, 2006
|
|
2F86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f86 by Molmil](/molmil-images/mine/2f86) | |
5HHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hhn by Molmil](/molmil-images/mine/5hhn) | Crystal Structure of HLA-A*0201 in complex with M1-F5L | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Gras, S, Josephs, T.M, Rossjohn, J. | Deposit date: | 2016-01-11 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3L2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l2w by Molmil](/molmil-images/mine/3l2w) | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and GS9137 (Elvitegravir) | Descriptor: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', 6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... | Authors: | Hare, S, Gupta, S.S, Cherepanov, P. | Deposit date: | 2009-12-15 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
|
|
5HHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hhq by Molmil](/molmil-images/mine/5hhq) | Crystal Structure of HLA-A*0201 in complex with M1-L3W | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Gras, S, Josephs, T.M, Rossjohn, J. | Deposit date: | 2016-01-11 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6A4L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a4l by Molmil](/molmil-images/mine/6a4l) | AcrR from Mycobacterium tuberculosis | Descriptor: | SODIUM ION, SULFATE ION, TetR family transcriptional regulator | Authors: | Kang, S.M. | Deposit date: | 2018-06-20 | Release date: | 2019-06-26 | Last modified: | 2020-04-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism. Febs Open Bio, 9, 2019
|
|
2PNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2png by Molmil](/molmil-images/mine/2png) | Type I rat fatty acid synthase acyl carrier protein (ACP) domain | Descriptor: | Fatty acid synthase (EC 2.3.1.85) | Authors: | Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P. | Deposit date: | 2007-04-24 | Release date: | 2007-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains. J.Biol.Chem., 283, 2008
|
|
2QMJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qmj by Molmil](/molmil-images/mine/2qmj) | Crystral Structure of the N-terminal Subunit of Human Maltase-Glucoamylase in Complex with Acarbose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2007-07-16 | Release date: | 2008-01-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity J.Mol.Biol., 375, 2008
|
|
6A1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a1q by Molmil](/molmil-images/mine/6a1q) | Crystal structures of disordered Z-type helices | Descriptor: | DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*G)-3') | Authors: | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | Deposit date: | 2018-06-07 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
|
|
3LPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lpu by Molmil](/molmil-images/mine/3lpu) | HIV integrase | Descriptor: | (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ... | Authors: | Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z. | Deposit date: | 2010-02-06 | Release date: | 2010-05-12 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat.Chem.Biol., 6, 2010
|
|
2OWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oww by Molmil](/molmil-images/mine/2oww) | Covalent intermediate in amylomaltase in complex with the acceptor analog 4-deoxyglucose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-alpha-glucanotransferase, 4-deoxy-alpha-D-glucopyranose, ... | Authors: | Barends, T.R.M, Bultema, J.B, Kaper, T, van der Maarel, M.J.E.C, Dijkhuizen, L, Dijkstra, B.W. | Deposit date: | 2007-02-17 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase. J.Biol.Chem., 282, 2007
|
|
6A4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a4w by Molmil](/molmil-images/mine/6a4w) | AcrR from Mycobacterium tuberculosis | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | Authors: | Kang, S.M, Kim, D.H. | Deposit date: | 2018-06-21 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.587 Å) | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism. Febs Open Bio, 9, 2019
|
|
2D0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d0k by Molmil](/molmil-images/mine/2d0k) | |
1RFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rfi by Molmil](/molmil-images/mine/1rfi) | Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, pentapeptide KLNYK, and tetranucleotide AGTC | Descriptor: | 5'-D(*AP*GP*TP*C)-3', SPERMINE, Topoisomerase I-Derived Peptide, ... | Authors: | Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G. | Deposit date: | 2003-11-10 | Release date: | 2004-03-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. J.Med.Chem., 47, 2004
|
|
5RUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5rup by Molmil](/molmil-images/mine/5rup) | PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000004976927 | Descriptor: | Non-structural protein 3, [3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]acetic acid | Authors: | Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. | Deposit date: | 2020-09-28 | Release date: | 2020-12-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
|
|
2LPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lpk by Molmil](/molmil-images/mine/2lpk) | Solution NMR of the specialized apo-acyl carrier protein (RPA2022) from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR324 | Descriptor: | Specialized acyl carrier protein | Authors: | Ramelot, T.A, Rossi, P, Yang, Y, Lee, H, Ertekin, A, Wang, H, Ciccosanti, C, Kohan, E, Maglaqui, M, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-14 | Release date: | 2012-02-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations. Biochemistry, 51, 2012
|
|
2QEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qex by Molmil](/molmil-images/mine/2qex) | |
4LBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lbf by Molmil](/molmil-images/mine/4lbf) | |
2LE6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2le6 by Molmil](/molmil-images/mine/2le6) | Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface | Descriptor: | DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | Authors: | Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T. | Deposit date: | 2011-06-10 | Release date: | 2011-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity Nucleic Acids Res., 2011
|
|
4LV7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lv7 by Molmil](/molmil-images/mine/4lv7) | Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase E82C/S142C | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Inositol-pentakisphosphate 2-kinase, ... | Authors: | Gosein, V, Miller, G.J. | Deposit date: | 2013-07-26 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conformational stability of inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) dictates its substrate selectivity. J. Biol. Chem., 288, 2013
|
|
3VFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vfu by Molmil](/molmil-images/mine/3vfu) | crystal structure of HLA B*3508 LPEP-P7Ala, peptide mutant P7-ala | Descriptor: | Beta-2-microglobulin, LPEP peptide from EBV, P7A, ... | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | Deposit date: | 2012-01-10 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
|
|
3VP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vp5 by Molmil](/molmil-images/mine/3vp5) | X-ray Crystal Structure of Wild Type HrtR in the Holo Form | Descriptor: | CACODYLATE ION, PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator | Authors: | Sawai, H, Sugimoto, H, Shiro, Y, Aono, S. | Deposit date: | 2012-02-23 | Release date: | 2012-07-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis. J.Biol.Chem., 287, 2012
|
|
1NA7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1na7 by Molmil](/molmil-images/mine/1na7) | |
3VFP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vfp by Molmil](/molmil-images/mine/3vfp) | crystal structure of HLA B*3508 LPEP158G, HLA mutant Gly158 | Descriptor: | ACETATE ION, Beta-2-microglobulin, LPEP peptide from EBV, ... | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | Deposit date: | 2012-01-10 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
|
|
4LYT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lyt by Molmil](/molmil-images/mine/4lyt) | |