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1ZFJ
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH; EC 1.1.1.205) FROM STREPTOCOCCUS PYOGENES
Descriptor: INOSINE MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID
Authors:Zhang, R, Evans, G, Rotella, F.J, Westbrook, E.M, Beno, D, Huberman, E, Joachimiak, A, Collart, F.R.
Deposit date:1999-03-29
Release date:2000-03-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase.
Biochemistry, 38, 1999
1ZG9
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Crystal Structure of 5-{[amino(imino)methyl]amino}-2-(sulfanylmethyl)pentanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
Descriptor: 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID, ZINC ION, procarboxypeptidase B
Authors:Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZHO
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The structure of a ribosomal protein L1 in complex with mRNA
Descriptor: 50S ribosomal protein L1, POTASSIUM ION, mRNA
Authors:Nevskaya, N, Tishchenko, S, Volchkov, S, Kljashtorny, V, Nikonova, E, Nikonov, O, Nikulin, A, Kohrer, C, Piendl, W, Zimmermann, R, Stockley, P, Garber, M, Nikonov, S.
Deposit date:2005-04-26
Release date:2006-05-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:New insights into the interaction of ribosomal protein L1 with RNA.
J.Mol.Biol., 355, 2006
1ZIO
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PHOSPHOTRANSFERASE
Descriptor: ADENYLATE KINASE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
Authors:Berry, M.B, Phillips Jr, G.N.
Deposit date:1996-06-07
Release date:1997-07-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+.
Proteins, 32, 1998
1ZJD
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Kunitz Protease Inhibitor Domain of Protease Nexin II
Descriptor: Catalytic Domain of Coagulation Factor XI, Kunitz Protease Inhibitory Domain of Protease Nexin II
Authors:Jin, L, Navaneetham, D, Pandey, P, Strickler, J.E, Babine, R.E, Walsh, P.N, Abdel-Meguid, S.S.
Deposit date:2005-04-28
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
J.Biol.Chem., 280, 2005
1Z94
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X-Ray Crystal Structure of Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR12.
Descriptor: conserved hypothetical protein
Authors:Kuzin, A, Vorobiev, S.M, Yong, W, Forouhar, F, Xio, R, Ma, L.-C, Acton, T, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-03-31
Release date:2005-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Hypothetical Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CVR12.
To be Published
1ZM1
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Crystal structures of complex F. succinogenes 1,3-1,4-beta-D-glucanase and beta-1,3-1,4-cellotriose
Descriptor: Beta-glucanase, CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose
Authors:Tsai, L.C, Shyur, L.F, Cheng, Y.S, Lee, S.H.
Deposit date:2005-05-10
Release date:2006-05-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase in complex with beta-1,3-1,4-cellotriose
J.Mol.Biol., 354, 2005
1ZC6
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Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum. Northeast Structural Genomics Target Cvr23.
Descriptor: probable N-acetylglucosamine kinase
Authors:Vorobiev, S.M, Kuzin, A, Forouhar, F, Abashidze, M, Acton, T.B, Xiao, R, Ma, L.-C, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-04-11
Release date:2005-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum
To be Published
1Z6E
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Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
Descriptor: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation factor X
Authors:Alexander, R.S.
Deposit date:2005-03-22
Release date:2006-03-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.
J.Med.Chem., 48, 2005
1ZA6
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The structure of an antitumor CH2-domain-deleted humanized antibody
Descriptor: IGG Heavy chain, IGG Light chain
Authors:Larson, S.B, Day, J.S, Glaser, S, Braslawsky, G, McPherson, A.
Deposit date:2005-04-05
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of an Antitumor C(H)2-domain-deleted Humanized Antibody.
J.Mol.Biol., 348, 2005
1Z9J
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Photosynthetic Reaction Center from Rhodobacter sphaeroides
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ...
Authors:Thielges, M, Uyeda, G, Camara-Artigas, A, Kalman, L, Williams, J.C, Allen, J.P.
Deposit date:2005-04-02
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Design of a Redox-Linked Active Metal Site: Manganese Bound to Bacterial Reaction Centers at a Site Resembling That of Photosystem II
Biochemistry, 44, 2005
1ZI6
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Crystal Structure Analysis of the dienelactone hydrolase (C123S) mutant- 1.7 A
Descriptor: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION
Authors:Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L.
Deposit date:2005-04-27
Release date:2005-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
20GS
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GLUTATHIONE S-TRANSFERASE P1-1 COMPLEXED WITH CIBACRON BLUE
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CIBACRON BLUE, GLUTATHIONE S-TRANSFERASE
Authors:Oakley, A.J, Lo Bello, M, Nuccetelli, M, Mazzetti, A.P, Parker, M.W.
Deposit date:1997-12-16
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
J.Mol.Biol., 291, 1999
1ZPT
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Escherichia coli Methylenetetrahydrofolate Reductase (reduced) complexed with NADH, pH 7.25
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Pejchal, R, Sargeant, R, Ludwig, M.L.
Deposit date:2005-05-17
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of NADH and CH(3)-H(4)Folate Complexes of Escherichia coli Methylenetetrahydrofolate Reductase Reveal a Spartan Strategy for a Ping-Pong Reaction
Biochemistry, 44, 2005
1ZTJ
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide
Descriptor: 2-(5-BENZYLAMINO-2-METHYLSULFANYL-6-OXO-6H-PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-ACETAMIDE, BICARBONATE ION, Coagulation factor XI, ...
Authors:Nagafuji, P, Jin, L, Rynkiewicz, M, Quinn, J, Bibbins, F, Meyers, H, Babine, R.E, Strickler, J.E, Abdel-Meguid, S.S.
Deposit date:2005-05-27
Release date:2006-05-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Pyrimidinone Inhibitors of a Thrombolytic Protease
To be Published
2E3C
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BU of 2e3c by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase
Descriptor: Pyrrolysyl-tRNA synthetase
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-11-22
Release date:2007-12-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
J.Mol.Biol., 378, 2008
1ZZB
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Crystal Structure of CoII HppE in Complex with Substrate
Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, COBALT (II) ION, Hydroxypropylphosphonic Acid Epoxidase
Authors:Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L.
Deposit date:2005-06-13
Release date:2005-07-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
1ZZR
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Rat nNOS D597N/M336V double mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE, ...
Authors:Li, H, Flinspach, M.L, Igarashi, J, Jamal, J, Yang, W, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZTD
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Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
Descriptor: Hypothetical Protein Pfu-631545-001
Authors:Fu, Z.-Q, Horanyi, P, Florence, Q, Liu, Z.-J, Chen, L, Lee, D, Habel, J, Xu, H, Nguyen, D, Chang, S.-H, Zhou, W, Zhang, H, Jenney Jr, F.E, Sha, B, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-05-26
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
To be Published
1ZTL
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide
Descriptor: Coagulation factor XI, N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-2-{6-OXO-5-[(QUINOLIN-8-YLMETHYL)-AMINO]-2-M-TOLYL-6H-PYRIMIDIN-1-YL}-ACETAMIDE, SULFATE ION
Authors:Nagafuji, P, Jin, L, Rynkiewicz, M, Quinn, J, Bibbins, F, Meyers, H, Babine, R, Strickler, J.E, Abdel-Meguid, S.S.
Deposit date:2005-05-27
Release date:2006-05-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pyrimidinone Inhibitors of a Thrombolytic Protease
To be Published
2EAQ
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Crystal structure of PDZ domain of KIAA0858 (LIM), MS0793 from Homo sapiens
Descriptor: LIM domain only protein 7, NICKEL (II) ION
Authors:Xie, Y, Kishishita, S, Murayama, K, Takemoto, C, Shirozu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-01-31
Release date:2007-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Crystal structure of PDZ domain of KIAA0858 (LIM), MS0793 from Homo sapiens
To be Published
1ZRN
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INTERMEDIATE STRUCTURE OF L-2-HALOACID DEHALOGENASE WITH MONOCHLOROACETATE
Descriptor: ACETIC ACID, L-2-HALOACID DEHALOGENASE
Authors:Li, Y.-F, Hata, Y, Fujii, T, Hisano, T, Nishihara, M, Kurihara, T, Esaki, N.
Deposit date:1998-03-03
Release date:1999-03-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structures of reaction intermediates of L-2-haloacid dehalogenase and implications for the reaction mechanism.
J.Biol.Chem., 273, 1998
1XVQ
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Crystal structure of thiol peroxidase from Mycobacterium tuberculosis
Descriptor: AMMONIUM ION, YTTRIUM (III) ION, thiol peroxidase
Authors:Rho, B.S, Pedelacq, J.D, Hung, L.W, Holton, J.M, Vigil, D, Kim, S.I, Park, M.S, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-10-28
Release date:2004-12-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Functional and Structural Characterization of a Thiol Peroxidase from Mycobacterium tuberculosis.
J.Mol.Biol., 361, 2006
2DXE
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Crystal structure of nucleoside diphosphate kinase in complex with GDP
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kato-Murayama, M, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-08-25
Release date:2007-02-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of nucleoside diphosphate kinase in complex with GDP
To be Published
1XXD
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Crystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin
Descriptor: Coagulation factor XI, Ecotin
Authors:Jin, L, Pandey, P, Babine, R.E, Gorga, J.C, Seidl, K.J, Gelfand, E, Weaver, D.T, Abdel-Meguid, S.S, Strickler, J.E.
Deposit date:2004-11-04
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005

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数据于2024-07-17公开中

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