1XXD
Crystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin
Summary for 1XXD
Entry DOI | 10.2210/pdb1xxd/pdb |
Related | 1XX9 1XXF |
Descriptor | Coagulation factor XI, Ecotin (3 entities in total) |
Functional Keywords | fxia; catalytic domain; serine protein; ecotin, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P03951 Periplasm: P23827 |
Total number of polymer chains | 4 |
Total formula weight | 86124.14 |
Authors | Jin, L.,Pandey, P.,Babine, R.E.,Gorga, J.C.,Seidl, K.J.,Gelfand, E.,Weaver, D.T.,Abdel-Meguid, S.S.,Strickler, J.E. (deposition date: 2004-11-04, release date: 2004-11-16, Last modification date: 2023-08-23) |
Primary citation | Jin, L.,Pandey, P.,Babine, R.E.,Gorga, J.C.,Seidl, K.J.,Gelfand, E.,Weaver, D.T.,Abdel-Meguid, S.S.,Strickler, J.E. Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions J.Biol.Chem., 280:4704-4712, 2005 Cited by PubMed: 15545266DOI: 10.1074/jbc.M411309200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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